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Conformational states of methylamides of N-acetyl α-amino acids and their N-methyl derivatives IV. Association in solutions

Summary

1. The concentration dependences of the molecular weights and dipole moments of methylamides of N-acetyl α-amino acids and their N-methyl derivatives in chloroform have been studied.

2. The concentration limits at which the molecules are present in the unassociated state have been determined.

3. The jump-like nature of the concentration dependences of the molecular weights and dipole moments observed at the beginning of the association of the methylamides of N-acetyl-L-alanine and N-acetyl-L-valine is due to the dimerization of the folded conformations.

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Additional information

M. M. Shemyakin Institute of the Chemistry of Natural Compounds, Academy of Sciences of the USSR. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 354–363, May–June, 1973.

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Efremov, E.S., Kostetskii, P.V., Ivanov, V.T. et al. Conformational states of methylamides of N-acetyl α-amino acids and their N-methyl derivatives IV. Association in solutions. Chem Nat Compd 9, 334–340 (1973). https://doi.org/10.1007/BF00565691

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Keywords

  • Dipole Moment
  • Extended Form
  • Methylamides
  • Effective Dipole Moment
  • Dimeric Associate