Chemistry of Natural Compounds

, Volume 9, Issue 3, pp 334–340 | Cite as

Conformational states of methylamides of N-acetyl α-amino acids and their N-methyl derivatives IV. Association in solutions

  • E. S. Efremov
  • P. V. Kostetskii
  • V. T. Ivanov
  • E. M. Popov
  • Yu. A. Ovchinnikov
Article
  • 19 Downloads

Summary

1. The concentration dependences of the molecular weights and dipole moments of methylamides of N-acetyl α-amino acids and their N-methyl derivatives in chloroform have been studied.

2. The concentration limits at which the molecules are present in the unassociated state have been determined.

3. The jump-like nature of the concentration dependences of the molecular weights and dipole moments observed at the beginning of the association of the methylamides of N-acetyl-L-alanine and N-acetyl-L-valine is due to the dimerization of the folded conformations.

Keywords

Dipole Moment Extended Form Methylamides Effective Dipole Moment Dimeric Associate 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    E. S. Efremov, L. B. Senyavina, V. N. Zheltova, A. G. Ivanova, P. V. Kostetskii, V. T. Ivanov, E. M. Popov, and Yu. A. Ovchinnikov, Khim. Prirodn. Soedin.,9, 322 (1973).Google Scholar
  2. 2.
    V. T. Ivanov, P. V. Kostetskii, T. A. Balashova, S. L. Portnova, E. S. Efremov, and Yu. A. Ovchinnikov, Khim. Prirodn. Soedin.,9, 339 (1973).Google Scholar
  3. 3.
    E. S. Efremov, P. V. Kostetskii, V. T. Ivanov, E. M. Popov, and Yu. A. Ovchinnikov, Khim. Prirodn. Soedin.,9, 348 (1973).Google Scholar
  4. 4.
    L. L. Graham and C. Y. Chang, J. Phys. Chem.,75, 776 (1971).CrossRefGoogle Scholar
  5. 5.
    F. A. Momany, R. F. McGuire, J. F. Yan, and H. A. Scheraga, J. Phys. Chem.,74, 2424 (1970).CrossRefGoogle Scholar
  6. 6.
    E. M. Popov, G. M. Lipkind, S. F. Arkhipova, and V. G. Dashevskii, Molekul. Biol.,2, 622 (1968).Google Scholar
  7. 7.
    G. M. Lipkind, S. F. Arkhipova, and E. M. Popov, Zh. Strukt. Khim.,11, 121 (1970).Google Scholar
  8. 8.
    M. Davies and D. K. Thomas, J. Phys. Chem.,60, 763 (1956).CrossRefGoogle Scholar
  9. 9.
    M. Davies and H. E. Hallam, Trans. Faraday Soc.,47, 1170 (1951).CrossRefGoogle Scholar
  10. 10.
    W. Klemperer, M. W. Cronyn, A. H. Maki, and G. C. Pimentel, J. Amer. Chem. Soc.,76, 5846 (1954).CrossRefGoogle Scholar
  11. 11.
    J. Suzuki, M. Tsuboi, T. Shimanouchi, and S. Mizushima, Spektrochim. Acta,16, 471 (1960).CrossRefGoogle Scholar
  12. 12.
    S. Mizushima, T. Shimanouchi, S. Nakagura, K. Kuratani, M. Tsuboi, H. Baba, and O. Fujioka, J. Amer. Chem. Soc.,72, 3490 (1950).CrossRefGoogle Scholar
  13. 13.
    T. Ichikawa and Y. Iitaka, Acta Cryst. (B),25, 1824 (1969).CrossRefGoogle Scholar
  14. 14.
    S. Mizushima, T. Shimanouchi, M. Tsuboi, K. Kuratani, T. Sugita, N. Matag, and R. Sona, J. Amer. Chem. Soc.,75, 1863 (1953).CrossRefGoogle Scholar
  15. 15.
    U. Widmer and G. P. Lorenzi, Chimia,25, 236 (1971).Google Scholar
  16. 16.
    M. Goodman, F. Naider, and C. Toniolo, Biopolymers,10, 1719 (1971).CrossRefGoogle Scholar
  17. 17.
    J. Van Dam in: Characterisation of Macromolecular Structure, Proceedings of a Conference, April 5–7, 1967, Warrenton, Virginia, Washington (1969), p. 336.Google Scholar

Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • E. S. Efremov
  • P. V. Kostetskii
  • V. T. Ivanov
  • E. M. Popov
  • Yu. A. Ovchinnikov

There are no affiliations available

Personalised recommendations