Chemistry of Natural Compounds

, Volume 15, Issue 6, pp 743–747 | Cite as

Study of nucleic acid bases by the DADI method

  • R. Razakov
  • A. K. Kasimov
Article
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Abstract

The DADI spectra of the nucleic acid bases adenine (I), guanine (II), Uracil (III), thymine (IV), cytosine (V), and 5-methylcytosine (VI) have been studied. It has been established that the samples of nucleic acid bases investigated are characterized by a specific pattern of the DADI spectra which reflects the nature of the molecular ion due to the structure of the given base and, in the case of M+ for (IV) and (VI) also the tautomeric state. The possibility has been shown of using the information obtained for the quantitative determination of (VI) in a mixture of bases.

Keywords

Cytosine Thymine HNCO Nucleic Acid Basis Hydrocyanic Acid 

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Literature cited

  1. 1.
    J. L. Wilbbers, Anal. Biochem.,51, 542 (1973).CrossRefGoogle Scholar
  2. 2.
    A. M. Lawson, R. N. Stillwell, M. M. Tacker, K. Tsubojama, and J. A. McCloskey, J. Am. Chem. Soc.,94, 1014 (1971).Google Scholar
  3. 3.
    S. J. Show, D. M. Desiderio, T. Tsubojama, and J. A. McCloskey, J. Am. Chem. Soc.,92, 2510 (1970).CrossRefGoogle Scholar
  4. 4.
    J. M. Rise and G. O. Dudec, J. Am. Chem. Soc.,89, 2719 (1967).CrossRefGoogle Scholar
  5. 5.
    D. H. Smith, C. Djerassi, K. H. Maurer, and U. Rapp, J. Am. Chem. Soc.,96, 3482 (1974).CrossRefGoogle Scholar
  6. 6.
    R. Razakov, Kh. A. Aslanov, A. S. Sadykov, and B. V. Rozynov, Bioorgan. Khim.,3, 600 (1977).Google Scholar
  7. 7.
    J. Deutch, A. Razin, and J. Sedat, Anal. Biochem.,72, 586 (1976).CrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • R. Razakov
  • A. K. Kasimov

There are no affiliations available

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