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Alkaloids ofHaplophyllum dubium

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From the epigeal part ofHaplophyllum dubium we have isolated dubamine, γ-fagarine, skimmianine, graveoline, haplopine, the new alkaloid norgraveoline, and the steroid β-sitosterol. This is the first time that γ-fagarine has been found in this plant. On the basis of the results of a study of spectral characteristics and also passage to the known alkaloid graveoline, it has been established that norgraveoline has the structure of 2-piperonyl-4-quinolone.

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Additional information

Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 810–812, November–December, 1979.

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Razakova, D.M., Bessonova, I.A. & Yunusov, S.Y. Alkaloids ofHaplophyllum dubium . Chem Nat Compd 15, 716–718 (1979). https://doi.org/10.1007/BF00565570

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  • Alkaloid
  • Epigeal Part
  • Neutral Fraction
  • Dimethyl Sulfate
  • Diterpene Alkaloid