Steric effects in the iodomethylation of spatial isomers of matridine
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Only that nitrogen atom of a heterocyclic molecule can take part in the iodomethylation reaction for which a methyl group, after addition to it, undergoes no steric hindrance.
The rapid thermolysis of the methiodides of the isomers studied leads to partial demethylation without the decomposition of the molecule of the base itself.
KeywordsNitrogen Atom Methyl Iodide Initial Base Thermolysis Product Methiodide
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