Chemistry of Natural Compounds

, Volume 6, Issue 1, pp 48–51 | Cite as

Steroids

XXXVII. The stereospecificity of the hydrogenation of 16α-methyl-3-oxo-Δ4-unsaturated compounds
  • V. F. Shner
  • V. L. Sadovskaya
  • N. N. Suvorov
Article
  • 26 Downloads

Conclusions

1. It has been established that the hydrogenation of 11α-hydroxy-16α-methylpregn-4-ene-3,20-dione and of 16α-methylpregn-4-ene-3, 11 20-trione over 10% palladium on calcium carbonate in pyridine takes place stereospecifically and is determined by the substituent at C11.

2. It has been shown that a 16α-methyl group has practically no influence on the stereochemical directivity of the hydrogenation of the ethylenic bond of the Δ4-3-oxo system.

Keywords

Dione Intensive Formation Anhydrous Pyridine Ethylenic Bond Pyridine Solution 

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Copyright information

© Consultants Bureau 1972

Authors and Affiliations

  • V. F. Shner
    • 1
    • 2
  • V. L. Sadovskaya
    • 1
    • 2
  • N. N. Suvorov
    • 1
    • 2
  1. 1.Ordzhonikidze All-Union Scientific-Research Chemical and Pharmaceutical InstituteUSSR
  2. 2.Institute of the Chemistry of Natural Compounds, AS USSRUSSR

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