Plasma levels after a single oral dose of proscillaridin
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Summary
Plasma levels of proscillaridin, measured by a modified86Rb-erythrocyte method, have been studied in 6 healthy volunteers who received single oral doses of 2.5 mg. There were two maxima in the plasma curve, one after 0.5 h (median level 410 pg/ml) and another after 10 h (median value 390 pg/ml); and, a distinct minimum at 3 h (median value 98 pg/ml). After 24 h the median plasma concentration was 305 pg/ml, and after 48 h it was 115 pg/ml.
Key words
Cardiac glycosides proscillaridin plasma levels 86Rb-erythrocyte assayPreview
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References
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