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Über den histochemischen Leucin-Aminopeptidase-Nachweis in der menschlichen Skeletmuskulatur bei verschiedenen Myopathien

Histochemical evidence of leucine aminopeptidase activity in human skeletal muscle in myopathies

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With available histochemical methods, activity of leucine aminopeptidase is evident in human skeletal muscle only in those myopathies with proliferating connective tissue, not in normal muscle. In myopathy with proliferating connective tissue leucine aminopeptidase activity is only seen in the connective tissue, not however in the muscle fibre itself.


Der histochemische Nachweis einer Leucin-Aminopeptidaseaktivität gelingt in der menschlichen Skeletmuskulatur nur dann, wenn es im Rahmen der verschiedensten pathologischen Prozesse zur Entwicklung eines proliferierenden oder entzündlich infiltrierten Bindegewebes kommt.

Im Muskelparenchym läßt sich in der Regel keine Leucin-Aminopeptidase-Aktivität nachweisen.

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Mittelbach, F., Pongratz, D. Über den histochemischen Leucin-Aminopeptidase-Nachweis in der menschlichen Skeletmuskulatur bei verschiedenen Myopathien. Virchows Arch. Abt. A Path. Anat. 346, 68–73 (1969). https://doi.org/10.1007/BF00548468

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