Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Conversion of 5-hydroxy to 5-amino and 5-alkoxypyrazolidines

  • 38 Accesses


1-Acyl-5-hydroxypyrazolidines readily exchange their hydroxyl group when treated with primary amines or alcohols to form the corresponding 5-amino or 5-alkoxypyrazolidines. An acid catalyst is needed for the preparaton of the 5-alkoxypyrazolidines.

This is a preview of subscription content, log in to check access.

Literature Cited

  1. 1.

    K. N. Zelenin, A. V. Dovgilevich, I. P. Bezhan, G. A. Golubeva, L. A. Sviridova, L. V. Pastushenkov, E. G. Gromova, T. A. Gatchina, and S. V. Pomogaibo, Khim. Geterotsikl. Soedin., No. 5, 659 (1984).

  2. 2.

    K. N. Zelenin, G. A. Golubeva, S. V. Afanas'eva, L. A. Sviridova, I. P. Bezhan, M. Yu. Malov, and Yu. G. Bundel', Khim. Geterotsikl. Soedin., No. 9, 1238 (1985).

  3. 3.

    A. V. Dovgilevich, K. N. Zelenin, A. A. Espenbetov, Yu. T. Struchkov, I. P. Bezhan, L. A. Sviridova, G. A. Golubeva, M. Yu. Malov, and Yu. G. Bundel', Khim. Geterotsikl. Soedin., No. 9, 1242 (1985).

Download references

Author information

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 484–487, April, 1987.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Sviridova, L.A., Afanas'eva, S.V., Zelenin, K.N. et al. Conversion of 5-hydroxy to 5-amino and 5-alkoxypyrazolidines. Chem Heterocycl Compd 23, 403–406 (1987).

Download citation


  • Alcohol
  • Hydroxyl
  • Organic Chemistry
  • Acid Catalyst
  • Primary Amine