Zeitschrift für Krebsforschung

, Volume 63, Issue 1, pp 12–17 | Cite as

Über die Schädigung von Rattentumoren durch Ischämie

  • K. Letnansky
  • F. M. Allen


Mittels Unterbindung des Kreislaufs von tumortragenden Rattenbeinen wurde versucht, eine spezifische Schädigung der Tumorzellen zu erzielen. Als Maß für die Schädigung diente die Herabsetzung der Atmung und Milchsäurebildung in vitro. Der Zellstoffwechsel des Tumorgewebes wurde stärker geschädigt als der des Muskelgewebes.


By application of tourniquets, which occluded the flow of blood to the tumorbearing hind legs of rats, an attempt was made to injure specifically the tumor. The degree of the injury was determined by the reduction of the oxygen consumption and lactic acid production in vitro. The cellular metabolism of the tumor cells was injured much more than that of the muscle tissue.


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Copyright information

© Springer-Verlag 1959

Authors and Affiliations

  • K. Letnansky
    • 1
  • F. M. Allen
    • 1
  1. 1.Österreichischen Krebsforschungsinstitut WienWienÖstereich

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