Biochemical Genetics

, Volume 18, Issue 9–10, pp 947–954 | Cite as

Assignment to chromosome 16 of a gene necessary for the expression of human mitochondrial glutamate oxaloacetate transaminase (aspartate aminotransferase) (E.C.

  • E. Tolley
  • V. van Heyningen
  • R. Brown
  • M. Bobrow
  • I. W. Craig


A gene necessary for the expression of human mitochondrial glutamate oxaloacetate transaminase (GOT-2) has been assigned to chromosome 16 on the basis of an immunochemical analysis of human-mouse somatic cell hybrids. Mitochondrial GOT cosegregates with adenine phosphoribosyl transferase (E.C.

Key words

GOT-2 (E.C. somatic cells Chromosome 16 


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Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • E. Tolley
    • 1
  • V. van Heyningen
    • 2
  • R. Brown
    • 1
  • M. Bobrow
    • 1
  • I. W. Craig
    • 1
  1. 1.Genetics LaboratoryUniversity of OxfordOxfordEngland
  2. 2.MRC Cytogenetics UnitEdinburghScotland

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