Rat insulinoma cell line used as target for detection of islet cell surface antibodies in type I diabetics

  • M. Ziegler
  • W. Hildmann
  • Brigitte Ziegler
  • D. Michaelis
Posters A Immunological Analysis

Conclusion

The rat insulinoma line RIN-5AH-T2 has several advantages over the normal rat islet cells to detect ICSA:1. The RIN cell population is homogenous, whereas PRI cells contain other cell types in addition to B-cells; 2. large quantities of RIN cells can be easily prepared; 3. the rat insulinoma line should make it possible to compare more readily results from different laboratories.

Keywords

Analytical Chemistry Inorganic Chemistry Cell Surface Cell Population Islet Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Ratteninsulinom-Zellinie als Target für den Nachweis von Inselzelloberflächenantikörpern bei Typ -I-Diabetikern

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References

  1. 1.
    Bottazzo GF (1984) Diabetologia 26:241Google Scholar
  2. 2.
    Lernmark A (1985) Diabetologia 28:195Google Scholar
  3. 3.
    Van De Winkel M, Smets G, Gipts W, Pipeleers D (1982) J Clin Invest 70:41Google Scholar
  4. 4.
    Ziegler M, Ziegler B, Hehmke B (1984) Diabetologia 27:163Google Scholar

Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • M. Ziegler
    • 1
  • W. Hildmann
    • 1
  • Brigitte Ziegler
    • 1
  • D. Michaelis
    • 1
  1. 1.Central Institute of DiabetesKarlsburgGerman Democratic Republic

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