Evidence for linkage between four esterase loci in the rat (Rattus norvegicus)
Two new esterase polymorphisms have been described in tissue homogenates of the four rat strains August/Orl, LEW/Orl, Long Evans/Orl, and WAG/Orl. Independent expression of these polymorphisms in the different strains and in various tissues of a particular animal agrees with the separate genetic control hypothesis; the gene symbols Es-4 and Es-5 have been assigned to the loci. Transmission of both genes follows a normal autosomal recessive Mendelian pattern; preliminary data indicate tight linkage between these loci and the previously described Es-2 and Es-3 loci.
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- Augustinsson, K. B., and Henricson, B. (1966). A genetically controlled esterase in rat plasma. Biochim. Biophys. Acta 124323.Google Scholar
- Moutier, R., Toyama, K., and Charrier, M.-F. (1973). Biochemical polymorphism in the rat, Rattus norvegicus. Genetical study of four markers. Biochem. Genet. 8321.Google Scholar
- Petras, M. L., and Biddle, F. G. (1967). Serum esterases in the house mouse, Mus musculus. Can. J. Genet. Cytol. 9704.Google Scholar
- Popp, R. A. (1967). Linkage of Es-1 and Es-2 in the mouse. J. Hered. 58186.Google Scholar
- Popp, R. A., and Popp, D. M. (1962). Inheritance of serum esterases having different electrophoretic patterns among inbred strains of mice. J. Hered. 53111.Google Scholar
- Womack, J. E. (1971). Evidence for a second esterase locus in Rattus norvegicus. Genetics Suppl. 68: No. 1, Part 2.Google Scholar
- Womack, J. E. (1972). Genetic control of the major electrophoretic component of rat plasma esterase. J. Hered. 6341.Google Scholar