Biochemical Genetics

, Volume 6, Issue 2–3, pp 217–230

Levels of RNA and DNA in Drosophila melanogaster at different stages of development: A comparison between one bobbed and two phenotypically non-bobbed stocks

  • A. J. Howells

DOI: 10.1007/BF00486405

Cite this article as:
Howells, A.J. Biochem Genet (1972) 6: 217. doi:10.1007/BF00486405


A bobbed mutant stock of Drosophila melanogaster from which bobbed larvae, pupae, and flies can easily be selected is described in this paper. The RNA levels in these bobbed insects, whether expressed per insect or per milligram of tissue, are lower than in either a wild-type or a non-bobbed \(\overline {XX} Y\) control stock at all developmental stages investigated. However, the DNA levels, at all developmental stages are similar in both bobbed and non-bobbed insects. The results, which suggest that the maximum rate of ribosomal RNA synthesis and the average ribosome level per cell are lower than normal in these bobbed insects, are discussed in relation to the hypothesis that bobbed mutations bring about reduced rates of ribosome synthesis.

Copyright information

© Plenum Publishing Corporation 1972

Authors and Affiliations

  • A. J. Howells
    • 1
  1. 1.Department of Biochemistry, School of General StudiesAustralian National UniversityCanberraAustralia

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