Biochemical Genetics

, Volume 16, Issue 5–6, pp 593–607

Biochemical genetics of Fundulus heteroclitus (L.). I. Temporal and spatial variation in gene frequencies of Ldh-B, Mdh-A, Gpi-B, and Pgm-A

  • Dennis A. Powers
  • Allen R. Place

DOI: 10.1007/BF00484222

Cite this article as:
Powers, D.A. & Place, A.R. Biochem Genet (1978) 16: 593. doi:10.1007/BF00484222


Natural populations of Fundulus heteroclitus show extensive spatial variation in gene frequencies at four unlinked polymorphic loci. Large clinal changes in gene frequencies were found for Ldh-B, Mdh-A, and Gpi-B, whereas the spatial variation for the Pgm-B locus was small. Since the geographical area over which these clines are found is characterized by a steep thermal gradient, the clines in gene frequency are correlated with a directional change in mean water temperature. Maximum gene diversity of these four loci was correlated with annual fluctuations in water temperature. Temporal stability of the allelic frequencies was established for a 2–4 year period.

Key words

F. heteroclitus allozymes cline gene frequency environmental temperature 

Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • Dennis A. Powers
    • 1
  • Allen R. Place
    • 1
  1. 1.Department of BiologyThe Johns Hopkins UniversityBaltimore

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