, Volume 67, Issue 3, pp 157–159 | Cite as

Prevalence of pathogenic fungi in the toe-webs and toe-nails of diabetic patients

  • Isac Alteras
  • Ety Saryt


100 diabetic and 100 diabetes-free patients were mycologically examined for the presence of pathogenic fungi in their toe-webs and toe-nails. While there were clinical signs of presumed mycotic infection in 73 of the diabetic and in 66 of the non-diabetic subjects, the examination of the KOH-treated specimens revealed fungal elements in only 70 of the former and in 53 of the latter group. Isolation of the causative agent was possible in 57 of the diabetic patients (T. rubrum in 46%, C. albicans in 31%, T. mentagrophytes in 21% and E. floccosum in 3%) and in 40 of the control group (T. rubrum 57,5%, T. mentagrophytes 35%, C. albicans 5%, E. floccosum 2,5%). An interesting correlation was observed between the level of blood sugar and the percentage of positive fungal findings, the patients with more than 3000 mg/ml being 100% afected. C. albicans was found in a lower percentage in non-diabetic patients. The in vitro test of the sensitivity of the isolated organisms to the antidiabetic drugs, received by the patients, showed no significant anti-fungal activity.


Blood Sugar Sugar Clinical Sign Diabetic Patient Lower Percentage 
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100 malades avec diabète et 100 sujets sains ont été examinés au point de vue mycologique, en vue d'observer la présence des champignons pathogens dans les espaces interdigitaux des pieds et dans les ongles des orteils. Des signes suggérant une invasion fongique dans ces endroits ont été trouvés chez 73 des malades avec diabète et chez 66 des non-diabétiques. L'examen microscopique des squâmes et des ongles a mis en évidence la présence des élements fongiques chez 70 malades du premier groupe et chez 53 du lot témoin. L'agent causal a pu être isolé dans 57 cas du groupe diabétique et dans 40 groupe contrôle. Une correlation intéressante a été observée entre le taux du sucre et le pourcentage des resultats positifs. C. albicans a été trouvé dans une proportion mineure chez les sujets non-diabétiques. La sensibilité in vitro des agents isolés vis-à-vis des préparations anti-diabétiques utilisées n'a montré qu'une action antifongique insignifiante.


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Copyright information

© Kluwer Academic Publishers 1979

Authors and Affiliations

  • Isac Alteras
    • 1
  • Ety Saryt
    • 1
  1. 1.Department of DermatologyBeilinson Medical Center and Tel Aviv University Medical SchoolPetah TiqvaIsrael

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