Studies in the imidazole series
XLIX. Synthesis of derivatives of imidazo[2,1-b]thiazole
Article
Received:
- 24 Downloads
- 1 Citations
Abstract
A new synthesis of derivatives of imidazo[2,1-b]thiazole from 2-halogenoimidazoles has been effected. The reaction of 2-bromo-4,5-diphenylimidazoles with phenacyl bromide and its p-substituted derivatives has given the corresponding 2-bromo-1-phenylimidazoles, by the heating of which with thiourea and subsequent cyclization of the resulting 2-mercapto-1-phenacylimidazoles under the action of phosphorus oxychloride a number of 2,5,6-triarylimidazo[2,1-b]thiazoles has been synthesized.
Keywords
Phosphorus Bromide Organic Chemistry Imidazole Thiourea
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Preview
Unable to display preview. Download preview PDF.
Literature cited
- 1.I. A. Mazur and P. M. Kochergin, KhGS [Chemistry of Heterocyclic Compounds], 6, 512, 1970.Google Scholar
- 2.
- 3.E. Ochiai, Ber., 69, 1650, 1936.Google Scholar
- 4.P. M. Kochergin and M. N. Shchukina, ZhOKh, 26, 2905, 1956.Google Scholar
- 5.I. A. Mazur and P. M. Kochergin, KhGS [Chemistry of Heterocyclic Compounds], 6, 508, 1970.Google Scholar
- 6.A. Lawson and H. V. Morley, J. Chem. Soc., 1965, 1955; 566, 1957.Google Scholar
- 7.P. M. Kochergin, B. A. Priimenko, V. S. Ponomar, M. V. Povstyanoi, A. A. Tkachenko, I. A. Mazur, A. N. Krasovskii, E. G. Knysh, and M. I. Yurchenko, KhGS [Chemistry of Heterocyclic Compounds], 5, 177, 1969.Google Scholar
- 8.D. Harrison and T. Ralph, J. Chem. Soc., 3132, 1965.Google Scholar
- 9.J. D. Lamb and F. L. Pyman, J. Chem. Soc., 125, 706, 1924.Google Scholar
Copyright information
© Consultants Bureau 1973