Zur pathologischen Anatomie des Morbus Menière
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Histological findings on scarpa's ganglion and vestibular nerve, part II.
21 biopsy specimens show identical pathological changes, that is a reticular-diffuse or circumscribed dense fiber tissue arising from the original immature interstitial tissue. Some groups of ganglion cells are almost embedded in the plates of connective tissue. Thereby the distance from the single ganglion cell to the next ist more distant than normal. The nerves also show a thicking of the perineurium as compared with examination of normal vestibular nerves. Another pathological finding in the nerve is the severe degree of hyalinisation of the small arteries. In several instances the lumen of these vessels has been reduced to the diameter of a capillary. Perhaps there is a uniform pathogenesis, at first a disturbed blood supply, then a reactive proliferation of connective tissue and eventually the symptoms of Menière's disease.
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