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Basic study of nasal provocative test first report: Side, site of the nose, size of site and allergen amount

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The methodology of the provocative nasal test has varied according to the investigators. In order to establish a standard method of this test quantification of the nasal challenge, including the amount of the allergen, nasal site, side and size of allergen deposition, was studied. From the results obtained it is preferable to use the end point test and to apply allergen to the anterior part of the inferior turbinate in a 7mm2 size of surface area, bilaterally. An alternative test is to use a fixed amount of allergen (500 μg house dust in house dust allergy).

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Okuda, M. Basic study of nasal provocative test first report: Side, site of the nose, size of site and allergen amount. Arch Otorhinolaryngol 214, 241–246 (1977). https://doi.org/10.1007/BF00458318

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Key words

  • Nasal provocative test
  • Quantitative challenge
  • Different sensitivity of side and site