Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Enzyme activities involved in connective tissue metabolism in the skin of tight-skin (TSK) mice

  • 23 Accesses

  • 5 Citations

This is a preview of subscription content, log in to check access.

References

  1. 1.

    Blix G (1948) The determination of hexosamine according to Elson and Morgan. Acta Chem Scand [B] 2:467–473

  2. 2.

    Borooah J, Leadback DH, Walker PG (1961) Studies on glucosaminidase. 2. Substrates for N-acetyl-β-glucosaminidase. Biochem J 78:106–110

  3. 3.

    Buckingham RP, Prince PK, Rondnan GP, Taylor F (1978) Increased collage accumulation in dermal fibroblast cultures from patients with progressive systemic sclerosis (scleroderma). J Lab Clin Med 92:5–21

  4. 4.

    Edward CA, O'Brien WD (1980) Modified assay for the determination of hydroxyproline in a tissue hydrolysate. Clin Chim Acta 104:161–167

  5. 5.

    Fleckman PH, Jeffrey JJ, Eisern AZ (1973) A sensitive microassay for prolyl hydroxylase activity in normal and psoriatic skin. J Invest Dermatol 60:46–52

  6. 6.

    Green MC, Sweet OH, Bunker LE (1976) Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton. Am J Pathol 82:493–511

  7. 7.

    Jimenez SA, Millan A, Bashey RI (1984) Scleroderma-like alterations in collagen metabolism occurring in the TSK (tight skin) mouse. Arthritis Rheum 27:180–185

  8. 8.

    Kato K, Yoshida K, Tsukamoto H, Nobunaga M, Masuya T, Sawada T (1960) Synthesis of p-nitrophenyl β-d-glucopyranosiduronic acid and its utilization as a substrate for the assay of β-glucuronidase activity. Chem Pharm Bull (Tokyo) 8:239–242

  9. 9.

    Keiser HR, Stein HD, Sjoerdama A (1971) Increased protocollagen proline hydroxylase activity in sclerodermatous skin. Arch Dermatol 104:57–60

  10. 10.

    Kuutti-Savolainen E, Risteli J, Miettinen TA, Kivirikko KI (1979) Collagen biosynthesis enzymes in serum and hepatic tissue in liver disease. 1. Prolyl hydroxylase. Eur J Clin Invest 9:89–95

  11. 11.

    Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265–275

  12. 12.

    Ninomiya Y, Hata R, Nagai Y, Tajima S, Nishikawa T, Hatano H (1982) Glycosaminoglycan metabolism by scleroderma fibroblasts in culture. Biomed Res 3:70–83

  13. 13.

    Osborn TG, Bauer NE, Ross SC, Moore TL, Zuckner J (1983) The tight-skin mouse. Physical and biochemical properties of the skin. J Rheumatol 10:793–796

  14. 14.

    Peltonen L, Palotie A, Myllylä R, Krieg T, Oikarinen A (1985) Collagen biosynthesis in systemic scleroderma: regulation of posttranslational modifications and synthesis of procollagen in culture fibroblasts. J Invest Dermatol 84:14–18

  15. 15.

    Peterkofsky B, DiBlasio R (1975) Modification of the tritium-release asays for prolyl and lysyl hydroxylases using Dowex-50 columns. Anal Biochem 66:279–286

  16. 16.

    Rodnan GP, Lipinski E, Luksick J (1979) Skin thickness and collagen content in progressive systemic sclerosis and localized scleroderma. Arthritis Rheum 22:130–140

  17. 17.

    Roe JH (1955) The determination of sugar in blood and spinal fluid with anthrone reagent. J Biol Chem 212:335–343

  18. 18.

    Ross SC, Osborn TG, Dorner RW, Zuckner J (1983) Glycosaminoglycan content in skin of the tight-skin mouse. Arthritis Rheum 26:653–657

  19. 19.

    Shikata H, Utsumi N, Noguchi M, Asano T, Kashimata M, Hiramatsu M, Masumizu T (1985) Enzyme activities involved in collagen and proteoglycan degradation in oral mucosas of beige (Chediak-Higashi syndrome) mice. Arch Dermatol Res 227:430–431

  20. 20.

    Warren L (1959) The thiobarbituric acid assay of sialic acids. J Biol Chem 234:1971–1975

Download references

Author information

Correspondence to H. Shikata.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Shikata, H., Hiramatsu, M., Kashimata, M. et al. Enzyme activities involved in connective tissue metabolism in the skin of tight-skin (TSK) mice. Arch Dermatol Res 278, 510–512 (1986). https://doi.org/10.1007/BF00455176

Download citation

Key words

  • Collagen synthesis
  • Proteoglycan degradation
  • Skin
  • Tight-skin mouse