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The capsid antigen of Epstein-Barr virus in nasopharyngeal carcinomas: Comparison of serum antibody titre, cellular antigen content and histopathology

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Summary

In a retrospective study of 21 patients with nasopharyngeal malignancies (lymphoepithelial carcinomas, both undifferentiated and dedifferentiated serological and immunohistological methods were used to examine the significance of the IgG- and IgM-antibody against the capsid antigen of Epstein-Barr virus for early detection and follow-up, and the findings compared with those from a control group. Furthermore, the IgA-antibody is taken into account and presented with examples from the literature. Other possible forms of therapy (combined radio- and polychemotherapy) are also discussed.

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Falser, N. The capsid antigen of Epstein-Barr virus in nasopharyngeal carcinomas: Comparison of serum antibody titre, cellular antigen content and histopathology. Arch Otorhinolaryngol 239, 15–23 (1984). https://doi.org/10.1007/BF00454258

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Key words

  • Epstein-Barr virus
  • Nasopharyngeal carcinoma
  • Viral antigens
  • Virology