Treatment of idiopathic west and lennox-gastaut syndromes by intravenous administration of human polyvalent immunoglobulins

  • K. van Rijckevorsel-Harmant
  • M. Delire
  • M. Rucquoy-Ponsar
Original Articles


A total of 7 patients (3–21 years old) suffering from an intractable “primary” Lennox-Gastaut syndrome (LGS) were treated with i.v. high doses of polyvalent human immunoglobulins. Of these patients 6 improved following such treatment with a decrease in fits and an improvement in the EEG.

Hypotheses about the contribution of the treatment and immunopathological factors in some cases of idiopathic LGS are discussed.

Key words

Immunoglobulins Intractable epilepsy Lennox-Gastaut syndrome 


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Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • K. van Rijckevorsel-Harmant
    • 1
  • M. Delire
    • 2
  • M. Rucquoy-Ponsar
    • 3
  1. 1.Service de NeurophysiologieCentre Neurologique William LennoxOttignies
  2. 2.Department of Clinical ResearchHoechst-BehringBrussels
  3. 3.Service de NeuropédiatrieCentre Neurologique William LennoxOttigniesBelgium

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