Archives of Orthopaedic and Trauma Surgery

, Volume 109, Issue 4, pp 194–196 | Cite as

Hip implant evaluation in an arthritic animal model

  • T. W. Phillips
  • K. R. Gurr
  • D. R. Rao
Origilal Articles


Animal studies can provide important information in the evaluation of new techniques and prosthetic designs in orthopedics. As a prerequisite they must parallel as closely as possible the human conditions they are modeling. An arthritic sheep model simulating the human clinical situation has previously been designed and reported by Phillips and Gurr [10]. The present study introduces for the first time an approach that evaluates a prosthetic joint in an arthritic animal hip. Hemiresurfacing following the Tharies technique [1] was carried out unilaterally in 12 Suffolk sheep, and followed up for 2 years. Femoral loosening occurred in three cases. Only one of the 12 cases showed postoperative avascularity of the femoral head. Radiologic follow-up and histologic examination showed features consistently and strikingly similar to those seen in human practice. The sheep hip with simulated arthritis provides a sensitive, clinically reproducible model for the future study of other arthroplasty types and problems.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Amstutz HC, Thomas BJ, Jinnah R, Kim W, Grogan T, Yale C (1984) Treatment of primary osteoarthritis of the hip: a comparison of total joint and surface replacement arthroplasty. J Bone Joint Surg [Am] 66:228–241Google Scholar
  2. 2.
    Bell RS, Schatzker J, Fornasier VL, Goodman SB (1985) Study of implant failure in the Wagner resurfacing arthroplasty. J Bone Joint Surg [Am] 67:1165–1175Google Scholar
  3. 3.
    Capello WN, Misamore GW, Trancik TM (1984) The Indiana conservative (surface replacement) hip arthroplasty. J Bone Joint Surg [Am] 66:518–528Google Scholar
  4. 4.
    Chen P-Q, Turner TM, Ronnigen H, Galante J, Urban R, Rostoker W (1983) A canine cementless total hip prosthesis model. Clin Orthop 176:24–33Google Scholar
  5. 5.
    Freeman MAR, Bradley GW (1983) ICLH surface replacement of the hip: an analysis of the first 10 years. J Bone Joint Surg [Br] 65:405–411Google Scholar
  6. 6.
    Head WC (1981) Wagner surface replacement arthroplasty of the hip — analysis of fourteen failures in 41 hips. J Bone Joint Surg [Am] 63:420–427Google Scholar
  7. 7.
    Hedley AK, Clarke IC, Bloebaum RD, Moreland J, Gruen T, Coster I, Amstutz HC (1981) Viability and cement fixation of the femoral head in canine hip surface replacement. Proceedings of the Seventh Open Scientific Meeting of the Hip Society. Mosby, St Louis, pp 160–187Google Scholar
  8. 8.
    Jolley MN, Salvati EA, Brown GC (1982) Early results and complications of surface replacement of the hip. J Bone Joint Surg [Am] 64:366–377Google Scholar
  9. 9.
    More RC, Amstutz HC, Moreland JR, Tooke SM (1988) Acetabular reconstruction with a threaded screw-ring prosthesis for failed total hip replacement. Orthop Trans 12:661Google Scholar
  10. 10.
    Phillips TW, Gurr KR (1989) A preconditioned arthritic hip model. Arthroplasty 4:193–200Google Scholar
  11. 11.
    Phillips TW, Johnston G, Wood P (1987) Selection of an animal model for hip resurfacing. Arthroplasty 2:111–117Google Scholar
  12. 12.
    Postel M, Mekhaldi M (1987) Cup arthroplasty in the treatment of aseptic necrosis of the head of the femur. Int Orthop 11:295–300Google Scholar
  13. 13.
    Ritter MA, Gioe TJ (1986) Conventional versus resurfacing total hip arthroplasty: a long term prospective study of concomitant bilateral implantation of prostheses. J Bone Joint Surg [Am] 68:216–225Google Scholar
  14. 14.
    Wagner H (1975) The total joint surface replacement in hip joint — preliminary notice. Arch Orthop Unfallchir 82:101–106Google Scholar
  15. 15.
    Wiles P (1958) The surgery of the osteoarthritic hip. Br J Surg 45:488–497Google Scholar

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • T. W. Phillips
    • 1
    • 2
  • K. R. Gurr
    • 1
    • 2
  • D. R. Rao
    • 1
    • 2
  1. 1.The Orthopedic Research LaboratorySt. Joseph's Health CenterLondonCanada
  2. 2.The Division of Orthopedic SurgeryThe University of Western OntarioCanada

Personalised recommendations