A mutation of the ctsA locus of Aspergillus nidulans affects both the radial growth and conidiation of the mould when grown in the presence of citrate. The ctsA locus was allocated to linkage group IV but it recombines freely with inoB2 and pyroA4 (which are also in linkage group IV). It is recessive in heterozygous diploids. A possible role for this gene in maintaining membrane integrity is discussed.
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The authors are with the Departamento de Genética, FMRP-USP, Av. Bandeirantes, 3900, 14049 Ribeirão Preto, SP., Brazil.
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Pombeiro, S.R.C., Martinez-Rossi, N.M. & Rossi, A. Effect of citrate on radial growth and conidiation of the mould Aspergillus nidulans . World J Microbiol Biotechnol 7, 609–612 (1991). https://doi.org/10.1007/BF00452842
- Aspergillus nidulans
- citrate toxicity
- pH regulation