Aesthetic Plastic Surgery

, Volume 19, Issue 2, pp 131–135 | Cite as

Effect of large-volume liposuction on sex hormones and glucose- and lipid metabolism in females

  • Frode Samdal
  • Kåre I. Birkeland
  • Leiv Ose
  • Petter F. Amland


Nine consecutive patients who underwent syringe-assisted liposuction with a mean aspirate volume of 3633 mL (range: 1800–5500) had their lipids, lipoproteins, and sex hormones measured pre- and postoperatively. Seven of the patients also underwent an oral glucose tolerance test with measurements of insulin and C-peptide. The major finding was a significant increase in HDL cholesterol and apolipoprotein A1, while there was no significant change in sex hormones or glucose levels 9–12 months after the liposuction procedure. The results indicate that large-volume liposuction might decrease the risk of cardiovascular disease in these patients.

Key words

Liposuction Sex hormones Glucose metabolism Lipids-Lipoproteins 


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  1. 1.
    Björntorp P: Obesity and diabetes. In: Alberti KGMM, Krall LP (eds): The Diabetes Annual, Volume 5, Amsterdam: Elsvier, 1990Google Scholar
  2. 2.
    DeFronzo RA, Ferrannini E: Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidaemia, and atherosclerotic cardiovascular disease. Diabetes Care 14: 173, 1991Google Scholar
  3. 3.
    Denke MA, Sempos CT, Grundy SM: Excess body weight: an unrecognized cause of high blood cholesterol. Circulation 82: 228, 1990Google Scholar
  4. 4.
    Evans DJ, Hofmann RG, Kalkhoff RK, Kissebah AH: Relationship of body fat topography to insulin sensitivity and metabolic profiles in premenopausal women. Metabolism 33: 68, 1984Google Scholar
  5. 5.
    Fournier PF: Why the syringe and not the suction machine? J Dermatol Surg Oncol 14: 1062, 1988Google Scholar
  6. 6.
    Friedewald WT, Levy RJ, Fredrichson DS: Estimation of the concentration of low-density-lipoprotein cholesterol in plasma without the use of the preparative ultracentrifuge. Clin Chem 18: 499, 1972Google Scholar
  7. 7.
    Grazer FM: Body contouring. In: McCarthy XX (ed): Plastic Surgery. Philadelphia: W.B. Saunders, 1990, pp 3964–4028Google Scholar
  8. 8.
    Landin K, Lønnroth P, Krotkiewski M, Holm G, Smith U: Increased insulin resistance and fat cell lipolysis in obese but not lean women with a high waist/hip ratio. Eur J Clin Invest 20: 530, 1990Google Scholar
  9. 9.
    Lillioja S, Bogardus C, Mott DM, Kennedy AL, Knowler WC, Howard BV: Relationship between insulin-mediated glucose disposal and lipid metabolism in man. J Clin Invest 75: 1106, 1985Google Scholar
  10. 10.
    Peterson B: Gender-an important parameter in medical science. Ugeskr Laeger 155: 608, 1993Google Scholar
  11. 11.
    Riepponen P, Marnierni J, Rautaoja T: Immunoturbidimetric determination of apolipoproteins A-1 and B in serum. Scand J Clin Lab Invest 47: 739, 1987Google Scholar
  12. 12.
    Samdal F, Mjolnerod OK, Lundbom J, et al: Gynecomastia: investigation and surgical treatment. Tidsskr Nor Laegeforen 109: 3015, 1989Google Scholar
  13. 13.
    Samdal F, Amland PF, Bugge JF: Blood loss during liposuction using the tumescent technique. Aesth Plast Surg 18: 157–160, 1994Google Scholar
  14. 14.
    Thorell A, Efendic S, Gutniak M, Häggmark T, Ljungqvist O: Development of postoperative insulin resistance is associated with the magnitude of operation. Eur J Surg 159: 593, 1993Google Scholar
  15. 15.
    Wing R, Bunker C, Kuller L, Matthews A: Insulin, body mass index, and cardiovascular risk factors in premenopausal women. Arteriosclerosis 9: 479, 1989Google Scholar

Copyright information

© Springer-Verlag New York Inc 1995

Authors and Affiliations

  • Frode Samdal
    • 1
  • Kåre I. Birkeland
    • 1
  • Leiv Ose
    • 1
  • Petter F. Amland
    • 1
  1. 1.OsloNorway

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