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Acetone production by methylobacteria

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An accumulation of acetone was observed during the metabolism of ethane and products of ethane oxidation by washed suspensions of Methylosinus trichosporium OB3B. This strain possessed an acetoacetate decarboxylase and 3-hydroxybutyrate dehydrogenase, and a decline in poly-β-hydroxybutyric acid occurred under the same conditions as acetone formation. A pathway of acetone production from poly-β-hydroxybutyric acid via 3-hydroxybutyrate and acetoacetate was suggested.

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Thomson, A.W., O'Neill, J.G. & Wilkinson, J.F. Acetone production by methylobacteria. Arch. Microbiol. 109, 243–246 (1976). https://doi.org/10.1007/BF00446635

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Key words

  • Acetone production
  • Methylosinus
  • Poly-β-hydroxybutyrate
  • 3-Hydroxybutyrate dehydrogenase
  • Acetoacetate decarboxylase