Persistent low plasma vitamin E levels in premature infants surviving respiratory distress syndrome
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Abstract
Plasma vitamin E levels were determined serially in preterm infants surviving respiratory distress syndrome (RDS) and in premature infants without RDS (control). Vitamin E intakes of the RDS and control infant group were not significantly different. The results of the study show that preterm infants surviving RDS have a persistent low plasma vitamin E level throughout the first 8 weeks of life. In contrast, in premature infants without RDS the plasma vitamin E level gradually increases to the adult level throughout the first 8 weeks of life. It is concluded that data on plasma vitamin E levels in premature infants with and without RDS should not be pooled together to obtain reference values. It is further suggested that premature infants with RDS might need more supplemental vitamin E than premature infants without RDS.
Key words
Newborn Plasma vitamin E Respiratory distress syndromeAbbreviation
- RDS
respiratory distress syndrome
References
- 1.Bell EF, Filer LJ (1981) the role of vitamin E in the nutrition of premature infants. Am J Clin Nutr 34:414–422Google Scholar
- 2.Gutcher GR, Raynor WJ, Farrell PM (1984) An evaluation of vitamin E status in premature infants. Am J Clin Nutr 40:1078–1089Google Scholar
- 3.Huijbers WAR, Oosterbaan JA, Meskendorp-Haarsma TJ, Hardonk MJ, Molenaar I (1979) An ultrastructural and cytochemical study of membrane alternations in X-irradiated liver tissue from normal and vitamin E deficient ducklings. Radiat Res 78:502Google Scholar
- 4.Molenaar I, Hulsteart CE, Vos J, Hommes FA (1973) The implication of the membrane localisation of vitamin E for its function, uptake and absorption. In: Jonxis JHP, Visser HKA, Troelstra JA (eds) Therapeutic aspects of nutrition. Fourth Nutrition Symposium. Stenfort Kroese, Leiden, pp 41–55Google Scholar
- 5.Pryor WA (1976) The role of free radical reactions in biological systems. In: Pryor WA (ed) Free radicals in biology, vol I. Academic Press, New York, pp 1–49Google Scholar
- 6.Sato S, Shimura S, Hirose T, Maeda S, Kawakemi M, Takhishima T, Kimura S (1980) Effects of long-term ozone exposure and dietary vitamin E in rats. Tohoku J Exp Med 130:117Google Scholar
- 7.Simon C, Kiosz D, Hofman I (1980) Serum concentrations of vitamin E in healthy infants fed commercial milks. Eur J Pediatr 133:273–276Google Scholar
- 8.Tangney CC, McNair HM, Driskell JA (1981) Quantitation of individual tocopherols in plasma, platelets, lipids and livers by high-performance liquid chromatography. J Chromatogr 224:389–397Google Scholar