European Journal of Pediatrics

, Volume 148, Issue 2, pp 143–145 | Cite as

Serum creatinine and creatinine clearance in healthy neonates and prematures during the first 10 days of life

  • N. Gordjani
  • R. Burghard
  • J. U. Leititis
  • M. Brandis


Normal serum creatinine (Scr) and creatinine clearance (Ccr) values during the first 10 days of life were obtained in 63 very premature (28–32 weeks of gestation), premature (33–37 weeks) and term infants (38–42 weeks). Scr fell, and Ccr rose less markedly in the very premature infants. Scr was 80 μmol/l on the 1st day of life both in very premature and premature infants, and 77 μmol/l in full-term neonates. After 10 days, Scr was 73, 53 and 35 μmol/l respectively. There was an exponential correlation between Ccr and gestational age, indicating rapid maturation of glomerular function.

Key words

Serum creatinine Creatinine clearance Normal values Neonates Prematures 



serum creatinine


creatinine clearance


gestational age


glomerular filtration rate


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Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • N. Gordjani
    • 1
  • R. Burghard
    • 1
  • J. U. Leititis
    • 1
  • M. Brandis
    • 1
  1. 1.Abteilung für Kinderheilkunde der UniversitätMarburgFederal Republic of Germany

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