European Journal of Pediatrics

, Volume 141, Issue 1, pp 50–51 | Cite as

Circulating immune complex in the mucocutaneous lymphnode syndrome

  • A. Furuse
  • I. Matsuda
Short Communication


In 16 patients with mucocutaneous lymphnode syndrome (MCLS) during the first 2 weeks after the onset (acute phase) and 1 month after the onset (remission phase), measurement of the circulating immune complex (CIC) was performed by a C1q-binding assay (C1q-B.A.) and/or a Protein-A precipitation test (Protein-A P.T.). Seven out of 12 samples and four out of nine samples were shown to have raised levels of CIC in the acute phase with the C1q-B.A. and Protein-A P.T. test. In the remission phase, on the other hand, positive results were found in one out of six samples with the C1q-B.A. test and in three out of nine samples with the Protein-A P.T. test. High levels of CIC and disease activity were parallel. Our finding of a higher incidence of positive CIC in MCLS supports the possibility of the immunopathological mechanism.

Key words

Mucocutaneous lymphnode syndrome (MCLS) Kawasaki disease-Circulating immune complex (CIC) 


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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • A. Furuse
    • 1
  • I. Matsuda
    • 1
  1. 1.Department of PediatricsKumamoto University Medical SchoolKumamoto CityJapan

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