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Bleeding as the first symptom of extrahepatic biliary atresia

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Four cases of extrahepatic biliary atresia are reported. Each of these infants presented with haemorrhagic phenomena rather than with prolonged jaundice. The increased bleeding tendency was due to a vitamin K deficiency, probably caused by cholestasis-induced malabsorption. Therefore extrahepatic biliary atresia should be considered in each infant with a bleeding diathesis.

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aspartate transaminase


alanine aminotransferase


99mTechnetium-labelled iminodiacetic acid


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Correspondence to R. H. J. Houwen.

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Houwen, R.H.J., Bouquet, J. & Bijleveld, C.M.A. Bleeding as the first symptom of extrahepatic biliary atresia. Eur J Pediatr 146, 425–426 (1987). https://doi.org/10.1007/BF00444954

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Key words

  • Biliary atresia
  • Haemorrhage
  • Vitamin K