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Bleeding as the first symptom of extrahepatic biliary atresia

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Abstract

Four cases of extrahepatic biliary atresia are reported. Each of these infants presented with haemorrhagic phenomena rather than with prolonged jaundice. The increased bleeding tendency was due to a vitamin K deficiency, probably caused by cholestasis-induced malabsorption. Therefore extrahepatic biliary atresia should be considered in each infant with a bleeding diathesis.

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Abbreviations

Hb:

haemoglobin

SGOT:

aspartate transaminase

SGPT:

alanine aminotransferase

99mTc-IDA:

99mTechnetium-labelled iminodiacetic acid

References

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    Balistreri WF (1985) Neonatal cholestasis. J Pediatr 106:171–184

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    Hope PL, Hall MA, Millward-Sadler GH, Normand ICS (1982) Alpha-1-antitrypsin deficiency presenting as a bleeding diathesis in the newborn. Arch Dis Child 57:68–70

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    Poley JR, Bennett Humphrey G (1974) Bleeding disorder in an infant associated with anicteric hepatitis. Clin Pediatr 13:1045–1047

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    Verity CM, Carswell F, Scott GL (1983) Vitamin K deficiency causing infantile intracranial haemorrhage after the neonatal period. Lancet I:1439

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Author information

Correspondence to R. H. J. Houwen.

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Houwen, R.H.J., Bouquet, J. & Bijleveld, C.M.A. Bleeding as the first symptom of extrahepatic biliary atresia. Eur J Pediatr 146, 425–426 (1987). https://doi.org/10.1007/BF00444954

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Key words

  • Biliary atresia
  • Haemorrhage
  • Vitamin K