European Journal of Pediatrics

, Volume 136, Issue 3, pp 285–289 | Cite as

Unusual case of progressive systemic sclerosis with onset in early childhood and following infectious mononucleosis

  • J. Urano
  • H. Kohno
  • T. Watanabe
Original Investigations


A rare case of infantile progressive systemic sclerosis is reported. A Japanese girl suffered from infectious mononucleosis at the age of 1 year 3 months, and 5 months later she developed edema and sclerosis of the skin. She has been followed up for 4 years and now has grotesque features, with contractures of hands and feet due to advanced systemic sclerosis. The relationship between infectious mononucleosis and progressive systemic sclerosis is discussed.

Key words

Progressive systemic sclerosis Infectious mononucleosis 


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Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • J. Urano
    • 1
  • H. Kohno
    • 1
  • T. Watanabe
    • 1
  1. 1.Department of PediatricsTokyo Teishin HospitalTokyoJapan

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