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European Journal of Pediatrics

, Volume 140, Issue 4, pp 338–343 | Cite as

Periodic paralysis with cardiac arrhythmia

  • T. Yoshimura
  • M. Kaneuji
  • T. Okuno
  • M. Yoshioka
  • T. Ueda
  • H. Mikawa
  • T. Kowata
  • T. Kamiya
Case Reports

Abstract

In 1963, Klein et al. first described two girls with normokalemic periodic paralysis and cardiac arrhythmia. We have observed a 15-year-old girl with cardiac arrhythmia and normokalemia but with some features of hyperkalemic, periodic paralysis. The patient showed a waddling gait and Gower's sign. She had atrophy of the proximal muscles and deep tendon reflexes were reduced. Her ECG showed bigeminy with multifocal premature ventricular contractions. At the start of an episode of muscle weakness, the serum potassium concentration rose from 3.1 to 4.4 mEq/l. Muscle weakness was not provoked by intravenous administration of 45 g glucose or of 72 g glucose followed by 10 units of regular insulin. Muscle weakness was evoked by the ingestion of 4 g potassium chloride. During the provoked muscle weakness, the ECG showed normal sinus rhythm temporarily.

Key words

Periodic paralysis Arrhythmia Potassium 

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References

  1. 1.
    Brooke MH (1977) A clinician's view of neuro-muscular disease. Baltimore, Williams and Wilkins Co, pp 182–194Google Scholar
  2. 2.
    Chesson AJ Jr, Schochet SS Jr, Peters BH (1979) Biphasic periodic paralysis. Arch Neurol 36:700–704Google Scholar
  3. 3.
    Klein R, Ganelin R, Marks JF, Usher P, Richards C (1963) Periodic paralysis with cardiac arrhythmia. J Pediatr 62:371–385Google Scholar
  4. 4.
    Levitt LP, Rose LI, Dawson DM (1972) Hypokalemic periodic paralysis with arrhythmia. N Engl J Med 286:253–254Google Scholar
  5. 5.
    Lisak RP, Lebeau J, Tucker SH, Rowland LP (1972) Hyperkalemic periodic paralysis and cardiac arrhythmia. Neurology 22: 810–815Google Scholar
  6. 6.
    Pearson CM (1964) The periodic paralyses: Differential features and pathologic observations in permanent myopathic weakness. Brain 87:341–353Google Scholar
  7. 7.
    Stubbs WA (1976) Bidirectional ventricular tachycardia in familiar hypokalemic periodic paralysis. Proc R Soc Med 69: 223–224Google Scholar

Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • T. Yoshimura
    • 1
  • M. Kaneuji
    • 1
  • T. Okuno
    • 1
  • M. Yoshioka
    • 1
  • T. Ueda
    • 1
  • H. Mikawa
    • 1
  • T. Kowata
    • 2
  • T. Kamiya
    • 2
  1. 1.The Department of PediatricsKyoto UniversityKyoto CityJapan
  2. 2.The Department of Pediatrics of the National Cardiovascular CenterOsakaJapan

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