European Journal of Pediatrics

, Volume 135, Issue 3, pp 291–292

Familial occurrence of meconium ileus

  • Jean L. Allan
  • Melissa Robbie
  • P. D. Phelan
  • D. M. Danks
Original Investigations

DOI: 10.1007/BF00442105

Cite this article as:
Allan, J.L., Robbie, M., Phelan, P.D. et al. Eur J Pediatr (1981) 135: 291. doi:10.1007/BF00442105

Abstract

A recurrence rate for meconium ileus of 39% was found among C.F. affected siblings in a study of 488 families with at least one C.F. child born over a 24 year period. The recurrence rate was highly significant and indicated a familial trend for the occurrence of meconium ileus. The findings of the study support the existence of genetic heterogeneity in cystic fibrosis.

Key words

Meconium ileus Cystic fibrosis Genetic heterogeneity 

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • Jean L. Allan
    • 1
    • 2
  • Melissa Robbie
    • 1
    • 2
  • P. D. Phelan
    • 1
    • 2
  • D. M. Danks
    • 1
    • 2
  1. 1.Department of Thoracic MedicineRoyal Children's HospitalMelbourneAustralia
  2. 2.Department of PaediatricsUniversity of MelbourneAustralia

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