European Journal of Pediatrics

, Volume 147, Issue 5, pp 556–557 | Cite as

Ventricular septal defect with overriding aorta in trisomy-18

  • R. J. Moene
  • M. Sobotka-Plojhar
  • A. Oppenheimer-Dekker
  • D. Lindhout
Case Reports
Received:
Accepted:

Abstract

In a child with trisomy-18 prenatal echocardiography demonstrated the presence of a ventricular septal defect with overriding aorta. In a previous anatomical study of 18 hearts with this malformation we found a 50% concurrence rate with trisomy-18. In case of prenatal echocardiographic detection of a ventricular septal defect with overriding aorta, we advise thorough ultrasound examination for additional malformations as seen in trisomy-18; subsequently this procedure should be completed by cytogenetic analysis of amniotic cells.

Key words

Ventricular septal defect Overriding aorta Trisomy-18 
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Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • R. J. Moene
    • 1
  • M. Sobotka-Plojhar
    • 1
  • A. Oppenheimer-Dekker
    • 2
  • D. Lindhout
    • 3
  1. 1.Department of Paediatric CardiologyFree University HospitalAmsterdamThe Netherlands
  2. 2.Department of Anatomy and EmbryologyUniversity of LeidenLeidenThe Netherlands
  3. 3.Department of Clinical GeneticsErasmus UniversityRotterdamThe Netherlands

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