Naturwissenschaften

, Volume 69, Issue 2, pp 63–74 | Cite as

Vitamin B12 als biologisch aktive Modellsubstanz

  • Bolesław Zagalak
Article
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Abstract

A critical review on corrinoid biochemistry and physiology is presented. This includes: chemical synthesis of biologically important organocorrinoids and the correlation between their structures and coenzymatic activity; forms, distribution and transport of physiologically active corrinoids; methylcobalamin- and adenosylcobalamin-dependent enzymatic reactions and their physiological functions; and steric course of the adenosylcobalamin-dependent enzymatic rearrangements. Special attention is paid to the mechanisms of adenosylcobalamin-dependent enzymatic reactions.

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Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • Bolesław Zagalak
    • 1
  1. 1.Chemisches LaboratoriumUniversitäts-KinderklinikZürich

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