Zeitschrift für Kinderheilkunde

, Volume 101, Issue 1, pp 85–90 | Cite as

PTA-Mangel bei einem 4 Monate alten Säugling

  • W. Schenck
  • H.-J. v. Mengden
  • W. Künzer


Blutgerinnungsstörung angeborener PTA-Mangel 

PTA-deficiency in an infant


Report on the observation of PTA-deficiency in an infant with unilateral cleft lip and cleft premaxillary process. Plastic operation under substitution with 130 ml fresh plasma without bleeding complications.


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  1. 1.
    Biggs, R., and R. G. Macfarlane: Human Blood Coagulation. Oxford: Blackwell 1963.Google Scholar
  2. 2.
    Fisch, U.: Über einen neuen Accelerator der Blutthrombokinasebildung. Thrombos. Diathes. haemorrh. (Stuttg.) 2, 60 (1958).Google Scholar
  3. 3.
    Horowitz, H. I., W. P. Wilcox, and M. M. Fujimoto: Assay of Plasma thromboplastin antecedent (PTA) with artificially depletet normal plasma. Blood 20, 35 (1963).Google Scholar
  4. 4.
    Künzer, W., u. P. Schulz: Zur Altersabhängigkeit von Plasma-Thromboplastin-Antecedent (PTA, Faktor XI). Ann. paediat. (Basel) 205, 155 (1965).Google Scholar
  5. 5.
    Lewis, J. H., D. Walters, P. Didisheim, and W. R. Merchant: Application of continuous flow electrophoresis to the study of blood coagulation proteins and fibrinolytic enzyme system. I. Normal human materials. J. clin. Invest. 37, 1323 (1958).Google Scholar
  6. 6.
    Margolis, J.: The role of Hageman factor in plasma/surface reactions. In: K. H. Brinkhouse: Hemophilia and other Hemorrhagic States. Symposion Rome 1959, Univ. of N. C.Google Scholar
  7. 7.
    Mengden, H. J. v.: Plasma Thromboplastin Antecedent. Dissertation Freiburg 1966.Google Scholar
  8. 8.
    Rapaport, S. J., R. R. Proctor, M. J. Patch, and M. Yettra: The mode of inheritance of PTA-deficiency: Evidence for the existance of major PTA and minor PTA-deficiency. Blood 18, 149 (1961).Google Scholar
  9. 9.
    Ratnoff, O. D., and J. H. Rosenblum: Role of Hageman-factor in the initiation of clotting by glass. Evidence that glass frees Hageman-factor from inhibition. Amer. J. Med. 25, 160 (1958).Google Scholar
  10. 10.
    Rosenthal, R. L., O. H. Dreskin, and N. Rosenthal: New hemophilia-like disease caused by dificiency of a third plasma thromboplastin factor. Proc. Soc. exp. Biol. (N. Y.) 82, 171 (1953).Google Scholar
  11. 11.
    Soulier, J. P., and O. Prou-Wartelle: New date on Hageman factor and plasma thromboplastin antecedent. The role of contact the initial phase of blood coagulation. Brit. J. Haemat. 6, 88 (1960).Google Scholar

Copyright information

© Springer-Verlag 1967

Authors and Affiliations

  • W. Schenck
    • 1
  • H.-J. v. Mengden
    • 1
  • W. Künzer
    • 1
  1. 1.Universitäts-Kinderklinik Freiburg i. Br.Freiburg i. Br.Deutschland

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