European Journal of Pediatrics

, Volume 145, Issue 5, pp 442–445 | Cite as

Cloverleaf skull associated with Pfeiffer syndrome: pathology and management

  • R. A. Kroczek
  • W. Mühlbauer
  • I. Zimmermann
Case Reports

Abstract

The clinical and radiological findings in an infant with severe cloverleaf skull associated with a Pfeiffer syndrome are presented. The skull anomaly resulted in raised intracranial pressure and proptosis of the right eye within several weeks of birth. The child died at 3 months of age after subtotal craniectomy. At autopsy a detailed macroscopical and histological analysis of the skull base was conducted. The timing and value of surgery are discussed as well as the pathology of the cloverleaf skull anomaly.

Key words

Kleeblattschädel Cloverleaf skull Pfeiffer syndrome Treatment Histomorphology 

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Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • R. A. Kroczek
    • 1
  • W. Mühlbauer
    • 2
  • I. Zimmermann
    • 3
  1. 1.Children's Hospital of the UniversityMünchenGermany
  2. 2.Department of Plastic Surgery, Klinikum Rechts der IsarTechnical UniversityMünchenGermany
  3. 3.Department of PathologySädtisches Krankenhaus SchwabingMünchenGermany

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