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Sexual forms of yeasts in clinical samples

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Abstract

The sexual or teleomorphic state of yeasts has only been described in a few clinically involved species, mainly those of the Saccharomycetaceae family. With the aim of gathering information on their incidence in human pathology, a study has been made of a total of 2,135 strains isolated from clinical samples and cultivated in McClary agar. From these, 8 strains in teleomorphic state were identified: Kluyveromyces marxianus [1], Pichia anomala [2], Pichia farinosa [1], Pichia membranaefaciens [1] and Saccharomyces cerevisiae [3]. The two strains of P. anomala were responsible for fungemia; K. marxianus and the two strains of S. cerevisiae produced vaginitis; the other strains were oral cavity colonizers.

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References

  1. 1.

    Schmid KO. Zur Aetiologie der interstitiellen plasmocellulären Pneumonie (Saccharomykose) im Säuglingsalter. Frankf Z Pathol 1955; 66: 426–448.

  2. 2.

    Földvári F, Flórián E. Blastomycosis profunda glutealis. Trans St John's Hosp Dermatol Soc 1965; 51: 60–61.

  3. 3.

    Lutwick LL, Phaff HJ, Stevens DA. Kluyveromyces fragilis as an opportunistic fungal pathogen of man. Sabouraudia 1980; 18: 69–73.

  4. 4.

    McGinnis MR, Walker DH, Folds JD. Hansenula polymorpha infection in a child with chronic granulomatous disease. Arch Pathol Lab Med 1980; 104: 290–292.

  5. 5.

    Csillag A, Brandstein L, Faber V, Maczo J. Adatok a koraszulottkori interstitialis pneumonia koroktanahoz. Orv Hetil 1953; 94: 1303–1304.

  6. 6.

    Csillag A, Brandstein L. The role of Blastomyces in the aetiology of interstitial plasmocytic pneumonia of the premature infant. Acta Microbiol Hung 1954; 2: 179–190.

  7. 7.

    Wang CJK, Schwarz J. The etiology of interstitial pneumonia: identification as Hansenula anomala of a yeast isolated from lungs of infants. Mycopathol Mycol Appl 1958; 9: 299–306.

  8. 8.

    Kostiala AAI, Kostiala I. Susceptibility of fungi in mouth-rinse specimens from patients with haematological malignancies. J Med Microbiol 1984; 18: 249–254.

  9. 9.

    Milstoc M, Siddiqui NA. Fungemia due to Hansenula anomala. NY State J Med 1986; 86: 541–542.

  10. 10.

    Murphy N, Buchanan CR, Damjanovic V, Whitacker R, Hart CA, Cooke RWI. Infection and colonization of neonates by Hansenula anomala. Lancet 1986; 2: 291–293.

  11. 11.

    Nohinek B, Zee-Cheng CS, Barnes WG, Dall L, Gibbs HR. Infective endocarditis of a bicuspid aortic valve caused by Hansenula anomala. Am J Med 1987; 82: 165–168.

  12. 12.

    Winn RE, Velazco D, Johnson J. Fungal sepsis caused by Hansenula anomala. Program and abstracts of the Annual Meeting of the American Society for Microbiology, Washington DC, 1987; 403.

  13. 13.

    Haron E, Anaissie E, Dumphy F, McCredie K, Fainstein V. Hansenula anomala fungemia. Rev Infect Dis 1988; 6: 1182–1186.

  14. 14.

    Klein AS, Tortora GT, Malowitz R, Greene WH. Hansenula anomala: a new fungal pathogen. Arch Intern Med 1988; 148: 1210–1213.

  15. 15.

    Qadri SM, Al-Dayel F, Strampfer MJ, Cunha BA. Urinary tract infection caused by Hansenula anomala. Mycopathologia 1988; 104: 99–101.

  16. 16.

    Dickensheheets DL. Hansenula anomala infection. Rev Infect Dis 1989; 11: 507–508.

  17. 17.

    Muñoz P, García ME, Berenguer J, Bernaldo JCL, Bouza E. Catheter-related fungemia by Hansenula anomala. Arch Intern Med 1989; 149: 709–710.

  18. 18.

    López F, Martín G, Paz ML, Sanz MA. Infección por Hansenula anomala en leucemia aguda. Enf Infec Microbiol Clin 1990, 8: 363–364.

  19. 19.

    Badenhorst L, Botha PL, Janse van Rensburg MN. The incidence of hospital fungal infections yeast fungaemia. S Afr Med J 1991; 79: 302–303.

  20. 20.

    Moses A, Maayan S, Shvil Y, Dudin A, Ariel I, Thalji A, Polacheck I. Hansenula anomala infections in children: from asymptomatic colonization to tissue invasion. Pediatr Infect Dis J 1991; 10: 400–402.

  21. 21.

    Hirasaki S, Ijichi T, Fujita N, Araki S, Gotoh H, Nakagawa M. Fungemia caused by Hansenula anomala: successful treatment with fluconazole. Intern Med 1992; 31: 622–624.

  22. 22.

    Alter SJ, Farley J. Development of Hansenula anomala infection in a child receiving fluconazole therapy. Pediatr Infect Dis J 1994; 13: 158–159.

  23. 23.

    Reiersol S, Hoel J. Saccharomyces carlsbergensis, possibly a pathogen. Acta Pathol Microbiol Scand 1958; 44: 313–318.

  24. 24.

    Stein PD, Folkens AT, Hruska KA. Saccharomyces fungemia. Chest 1970; 58: 173–175.

  25. 25.

    Nicoli RM, Sempé M, Russo A. Un nouveau peuplement vaginal insolite: une levurose conjugale à la levure de panification. Ann Parasitol Hum Comp 1974; 49: 369–370.

  26. 26.

    Rubinstein E, Noriega ER, Simberkoff MS, Holzman R, Rahal JJ. Fungal endocarditis: analysis of 24 cases and review of the literature. Medicine 1975; 54: 331–344.

  27. 27.

    Jensen DP, Smith DL. Fever of unkneown origin secondary to brewer's yeast ingestion. Arch Intern Med 1976; 136: 332–333.

  28. 28.

    Eschete ML, West BC. Saccharomyces cerevisiae septicemia. Arch Intern Med 1980; 140: 1539.

  29. 29.

    Canafax DM, Mann HJ, Dougherty SH. Postoperative peritonitis due to Saccharomyces cerevisiae treated with ketoconazole. Drug Intell Clin Pharm 1982; 16: 698–699.

  30. 30.

    Dougherty SH, Simmons L. Postoperative peritonitis caused by Saccharomyces cerevisiae. Arch Surg 1982; 117: 248–249.

  31. 31.

    Eng RH, Drehmel R, Smith SM, Goldstein EJC. Saccharomyces cerevisiae infections in man. Sabouraudia 1984; 22: 403–407.

  32. 32.

    Horn R, Wong B, Kiehn TE, Armstrong D. Fungemia in a cancer hospital: changing frequency, earlier onset, and results of therapy. Rev Infect Dis 1985; 7: 646–655.

  33. 33.

    Cimolai N, Gill MJ, Church D. Saccharomyces cerevisiae fungemia: case report and review of the literature. Diagn Microbiol Infect Dis 1987; 8: 113–117.

  34. 34.

    Sethi N, Mandell W. Saccharomyces fungemia in a patient with AIDS. N Y State J Med 1988; 88: 278–279.

  35. 35.

    Wilson JD, Jones BM, Kinghorn GM. Bread making as a source of vaginal infection with Saccharomyces cerevisiae. Sex Transm Dis 1988; 15: 35–36.

  36. 36.

    Tawfik OW, Papasian CJ, Dixon AY, Potter LM. Saccharomyces cerevisiae pneumonia in a patient with acquired immunodeficiency syndrome. J Clin Microbiol 1989; 27: 1689–1691.

  37. 37.

    Aucott JN, Fayen J, Grossnicklas H, Morrisey A, Lederman MM, Salata RA. Invasive infection with Saccharomyces cerevisiae: report of three cases and review. Rev Infect Dis 1990; 12: 406–411.

  38. 38.

    Doyle MG, Pickering LK, O'Brien N, Hoots K, Benson JE. Saccharomyces cerevisiae infection in a patient with acquired immunodeficiency syndrome. Pediatr Infect Dis J 1990; 9: 850–851.

  39. 39.

    Nielsen H, Stenderup J, Bruun B. Fungemia with Saccharomycetaceae: report of four cases and review of the literature. Scand J Infect Dis 1990; 22: 581–584.

  40. 40.

    Agatensi L, Franchi F, Mondello F, Bevilacqua RL, Ceddia T, De Bernardis F, Cassone A. Vaginopathic and proteolytic Candida species in outpatients attending a gynaecology clinic. J Clin Pathol 1991; 44: 826–830.

  41. 41.

    Chertow GM, Marcantonio ER, Wells RG. Saccharomyces cerevisiae empyema in a patient with esophago-pleural fistula complicating variceal sclerotherapy. Chest 1991; 99: 1518–1519.

  42. 42.

    Sobel JD, Vazquez J, Lynch M, Meriwether C, Zervos MJ. Vaginitis due to Saccharomyces cerevisiae: Epidemiology, clinical aspects, and therapy. Clin Infect Dis 1993; 16: 93–99.

  43. 43.

    Wherspann P, Fullbrandt U. Yarrowia lipolytica (Wickerham et al) van der Walt and von Arx isolated from a blood culture. Mykosen 1985; 28: 217–222.

  44. 44.

    McClary DO, Nulty WL, Miller GR. Effect of potassium versus sodium in the sporulation of Saccharomyces. J Bacteriol 1959; 78: 362–368.

  45. 45.

    Paula CR, Sampaio MC, Birman EG, Siqueira AM. Oral yeasts in patients with cancer of the mouth, before and during radiotherapy. Mycopathologia 1990; 112: 119–124.

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Correspondence to Pedro García-Martos.

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García-Martos, P., Mira, J., Galán, F. et al. Sexual forms of yeasts in clinical samples. Mycopathologia 136, 67–70 (1996). https://doi.org/10.1007/BF00437497

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Key words

  • Yeasts
  • Ascospores
  • Kluyveromyces
  • Pichia
  • Saccharomyces