A series of clinical studies of histoplasmosis based on demonstrations of etiology led to descriptions of chronic pulmonary histoplasmosis, the principal type in adults, and amphotericin B as an effective therapy. A participant recreates the atmosphere of discovery during the contributions of a team comprising a mycologist, a surgeon and two physicians using cultures of exised lung and sputum to clearly identify cases of chronic pulmonary histoplasmosis. Subsequently cooperating physicians in several V.A. Hospitals carried out randomized studies of treatment, dosage, and side effects that established Amphotericin B as the sole curative therapy for chronic pulmonary histoplasmosis for 20 years.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Baum, A. & Schwarz, J., 1962. Chronic Pulmonary Histoplasmosis. American Journal of Medicine 33: 873–879.
Conant, N. F., Smith, D. T., Baker, R. D., Martin, S. D. & Calloway, J. L., 1944. Manual of Clinical Mycology. 1st Ed., Philadelphia, PA. W. B. Saunders and Co.
Furcolow, M. L., 1950. Further Observation On Histoplasmosis. Mycology and Bacteriology. Public Health Reports 65: 965–994.
Furcolow, M. L. & Brasher, C. A., 1954. Chronic Progressive (Cavitary) Pulmonary Histoplasmosis As A Problem in Tuberculosis Sanitoriums. American Review of Tuberculosis 73: 609.
Furcolow, M. L., 1963. Comparison of Treated and Untreated Severe Histoplasmosis. A National Communicable Disease Cooperative Mycoses Study. Journal of the American Medical Association 183: 823–829.
Goodwin, R. A., Owens, F. T., Snell, J. T., Hubbard, W. W., Buchanan, R. D., Terry, R. J. & Des Pres, R. M., 1976. Chronic Pulmonary Histoplasmosis. Medicine 55: 413–452.
Goodwin, R. A., Owens, F. T., Snell, J. T., Hubbard, W. W., Buchanan, R. D., Terry, R. J. & Des Pres, R. M., 1976. Chronic Pulmonary Histoplasmosis. Medicine 55: 445–446.
Johnson, H. E. & Batson, R., 1948. Benign Pulmonary Histoplasmosis: A Case Report with Brief Review of Literature. Diseases of the Chest 14: 157.
Meleney, H. E., 1940. Histoplasmosis (Reticulo-Endothelio-Cytomycosis) A Review. American Journal of Tropical Medicine 20: 603–616.
Seabury, J. H. & Dascomb, H. E., 1958. Experience with Amphotericin B for the Treatment of Systemic Mycoses. Archives of Internal Medicine 102: 96–101.
Sutliff, W. D., 1961. Histoplasmosis Cooperative Study I. Frequency of Histoplasmosis Among Adult Hospitalized Males. VA-Armed Forces Cooperative Study on Histoplasmosis. American Review of Respiratory Disease 84:663–668.
Sutliff, W. D., Hughes, F. U. E. & Burkett, L. L., 1953. Active Chronic Pulmonary Histoplasmosis. American Medical Association Archives of Internal Medicine 92: 571–586.
Sutliff, W. D., 1964. Histoplasmosis Cooperative Study II. Chronic Pulmonary Histoplasmosis Treated with and without Amphotericin B. American Review of Respiratory Disease 89: 641–650.
Sutliff, W. D., 1971. Therapeutic Trials of Amphotericin B for the Treatment of Histoplasmosis. Histoplasmosis. Proceedings of the Second National Conference. Charles C. Thomas, Springfield, Ill.
Sutliff, W. D., 1972. Histoplasmosis Cooperative Study V. Amphotericin B Dosage for Chronic Pulmonary Histoplasmosis. American Review of Respiratory Disease 105: 60–67.
Utz, J. P., Louria, D. B., Feder, M., Emmons, C. W. & McCullough, N. B., 1958. A report of clinical studies in the use of Amphotericin B in patients with systemic fungal disease. Antibiotics Annual. 685–701.
Utz, J. P., Tregor, A., McCullough, N. B. & Emmons, C. W., 1959. Amphotericin B: Intravenous use in patients with systemic fungal disease. Antibiotics Annual. 628–634.
Dr. Sutliff died March 19, 1983
About this article
Cite this article
Sutliff, W.D. Histoplasmosis in veterans administration hospitals in middle America. Mycopathologia 83, 57–62 (1983). https://doi.org/10.1007/BF00437414
- Clinical Study
- Effective Therapy
- Curative Therapy