An indirect immunofluorescence (IF) method using rabbit anti-Candida albicans was used to detect C. albicans in blood samples of 12 patients with systemic candidosis defined clinically, histologically and by blood cultures. Positive staining of C. albicans could be detected in all of the patients. The findings suggest that IF-method offers a more rapid method in the diagnosis of disseminated candidosis.
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De Repentigny L, Reiss E. Current trends in immunodiagnosis of candidiasis and aspergillosis. Rev Inf Dis 1984; 6: 301–12.
Drutz DJ. Antigen detection in fungal infections. N Eng J Med 1986; 314: 115–7.
Fisher JF, Trincher RC, Agel JF, Buxton TB, Walker CA, Johnson DH, Cormier RE, Chew WH, Rissing JP. Disseminated candidiasis: A comparison of two immunological techniques in the diagnosis. Am J Med Sci 1985; 290: 135–42.
Lehmann PF, Reiss E. Comparison of serum anti-Candida albicans mannan IgG levels in ELISA tests of a normal population and in diseased patients. Mycopathologia 1980; 2: 89–93.
Matthews R. Immunoblot analysis of serological response in systemic candidosis. Lancet 1984; 22/29: 1415–8.
Mecksroth KL, Reiss E, Keller JW. Detection of antibodies and antigenemia in leukemic patients with candidiasis by enzyme-linked immunosorbent assay. J Inf Dis 1981; 144:24–32.
Myerowitz RL, Pazin GJ, Allen CM. Disseminated candidiasis: change in incidence, underlying diseases, and pathology. Am J Clin Path 1977; 68: 29–38.
Quindos G, Ponton J, Cisterna R. Detection of antibodies to Candida albicans germ tube in the diagnosis of systemic candidiasis. Eur J Clin Microbiol 1987; 6: 142–6.
Richardson MD, Stubbins JM, Warnock DW. Rapid enzyme-linked immunosorbent assay (ELISA) for detection of IgG antibodies to Candida albicans. Mycopathologia 1983; 81:29–33.
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Reijula, K.E. Detection of Candida albicans in disseminated candidosis by immunofluorescence staining. Mycopathologia 106, 1–3 (1989). https://doi.org/10.1007/BF00436919
- Candida albicans