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Fungal colonization in patients with cancer of the upper respiratory tract

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Fungal opportunistic infections are a danger for immunocompromised hosts, such as patients with malignancies, especially in a hospital environment. We studied a group of patients with solid tumors of the respiratory tract on admission and after twenty days of hospitalization. Colonization by moulds and/or yeasts was frequently found.

Preventive measures should be applied to avoid colonization inside the hospital. The importance of overcrowding, sanitation and diet is pointed out.

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  1. 1.

    Aisner J, Schimpff SC, Sutherland JC, Joung VM, Weirnick PM: Torulopsis glabrata pneumonitis in patients with cancer. JAMA 230:584–585, 1974.

  2. 2.

    Aisner J, Schimpff SC, Sutherland JC, Joung VM, Weirnick PM: Torulopsis glabrata infections in patients with cancer: increasing incidence and relationship to colonization. Am J Med 61:23–25, 1976.

  3. 3.

    Aisner J, Kvols LK, Sickles EA: Transtracheal selective bronchial brushing for pulmonary infiltrates in patients with cancer. Chest 69:367–371, 1976.

  4. 4.

    Ajello L, Georg LK, Kaplan W, Kaufman L: Laboratory manual for medical mycology. Centers for Disease Control, Atlanta, Georgia.

  5. 5.

    Arx JA Von: The genera of fungi sporulating in pure culture. J. Cramer, Vaduz, 1974.

  6. 6.

    Berrow RL: Invasive aspergillosis of paranasal tissues in children with malignancies. J Pediatr 103:49–53, 1983.

  7. 7.

    Bodey JP: Candidiasis in cancer patients. Am J Med 77:13–19, 1984.

  8. 8.

    Cox F: Adherence of Candida albicans to buccal epithelial cells in children and adults. J Lab Clin Med 102:960–972, 1983.

  9. 9.

    De Gregorio MW, Lee WMF, Linker CA, Jacobs RA, Ries CA: Fungal infections in patients with acute leukemia. Am J Med 73:543–548, 1982.

  10. 10.

    Drake JE, Maibach HI: Candida and candidiasis. Postgrad Med 53:83–120, 1973.

  11. 11.

    Feld R, Bodey JP, Rodriguez V, Luna M: Causes of death in patients with malignant lymphoma. Am J Med Sci 268:97–106, 1974.

  12. 12.

    Gaines JD, Remmington JS: Disseminated candidiasis in the surgical patients. Surgery 72:730–736, 1972.

  13. 13.

    Gold J, Poston W: Systemic infection with Trichosporon cutaneum in a patient with acute leukemia. Cancer 48:2163–2167, 1981.

  14. 14.

    Hart PD: The compromised host and infections. Deep fungal infections. J Infect Dis 120:169–173, 1969.

  15. 15.

    Haught HM, Mers WG, Besehoner WE, Vaugman WP; Saval R: Colonization and infection with Trichosporon species in immunosuppressed host. J Infect Dis 147:199–203, 1983.

  16. 16.

    Jay SJ: Nosocomial infections. Med Clin N Amer 67:1251–1277, 1983.

  17. 17.

    Kostiala I: Acute fungal stomatitis in patients with hematologic malignancies: Quantity and species of fungi. J Infect Dis 146:101–105, 1982.

  18. 18.

    Kreger Van R: The Yeasts. A Taxonomic Study. Elsevier Science Publ BV, Amsterdam, 1984.

  19. 19.

    Inagaki J, Rodriguez V, Bodey GP: Cause of death in cancer patients. Cancer 33:568–573, 1974.

  20. 20.

    McGinnis MR: Laboratory handbook of medical mycology. Academic Press, New York, 1980.

  21. 21.

    Martin MV, Al-Tikriti V, Branley PA: Yeast flora of the mouth and skin during and after irradiation for oral and laryngeal cancer. J Med Microbiol 14:457–468, 1978.

  22. 22.

    Meunier C, Cruciani FM, Ersky JK: Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients. Eur J Cancer Clin Oncol 19:43–48, 1983.

  23. 23.

    Meyer RD, Young LS: Aspergillosis complicating neoplastic disease. Am J Med 54:6–15, 1973.

  24. 24.

    Mirsky HS, Cuttner J: Fungal infection in acute leukemia. Cancer 30:1348–1352, 1972.

  25. 25.

    Pennington JE: Aspergillus pneumonia in hematologic malignancy. Arch Inst Med 137:769–771, 1977.

  26. 26.

    Polonelli L, Morace G, Barcaioli BM, Cossu AL: Survey of Cryptococcus neoformans diffusion in Italy. Igiene Moderna 76:733–741, 1981.

  27. 27.

    Raper KB, Fennel DI: The genus Aspergillus, Robert E. Krieger Publishing Company, New York, 1977.

  28. 28.

    Rebell G, Taplin D: Dermatophytes. Their recognition and identification. University of Miami Press, Florida, 1970.

  29. 29.

    Rippon JW: Medical mycology. The pathogenic fungi and the pathogenic actinomycetes. WB Saunders Co, Philadelphia, 1982.

  30. 30.

    Robin B: Oral candidiasis in cancer patients. South Med J 77:312–314, 1984.

  31. 31.

    Romett JL, Mewnan RK: Aspergillosis of the nose and paranasal sinuses. Laringoscope 92:764–766, 1982.

  32. 32.

    Seeliger HPR, Scroeter G: Prevention of fungal infections in hospitalized patients. Immun Infect 12:143–150, 1984.

  33. 33.

    Shepherd MG: Candidiasis: An infectious disease of increasing importance. N Z Dent J 78:89–93, 1982.

  34. 34.

    Timothi E, Kiehn PD, Fitzroy F, Edwards MS: The prevalence of yeasts in clinical specimens from cancer patients. Am J Clin Pathol 73:518–521, 1980.

  35. 35.

    Wingard JR, Merz WG: Candida tropicalis: A major pathogen in immunocompromised patients. Ann Intern Med 91:539–543, 1979.

  36. 36.

    Young RC: Aspergillosis: The spectrum of the disease in 98 patients. Medicine (Baltimore) 49:147, 1970.

  37. 37.

    Young RC: Fungemia with compromised host resistance. Ann Intern Med 80:605, 1974.

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Vidotto, V., Clerico, M., Franzin, L. et al. Fungal colonization in patients with cancer of the upper respiratory tract. Mycopathologia 96, 97–101 (1986). https://doi.org/10.1007/BF00436667

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  • hospital infections
  • fungi
  • yeasts
  • epidemiology