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Phylogeny and molecular epidemiology of Sporothrix schenckii in Japan


Mitochondrial DNA(mtDNA) diversity was investigated in 257 clinical isolants of Sporothrix schenckii obtained from 4 districts in Japan. S. schenckii was classified into 10 types based on Hae III restriction profiles. Phylogeny of types constructed by the method of Fitch and Margoliash [1] on the estimated sequence divergence within mtDNA using the methods of Nei and Li [2], showed that S. schenckii are grouped into 2 clusters, one group consisting of types 1, 2 and 3, and the other group consisting of the other seven types. In addition, types 1, 2, and 5 were correlated with their geographic origin, whereas type 4 was present throughout Japan.

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Takeda, Y., Kawasaki, M. & Ishizaki, H. Phylogeny and molecular epidemiology of Sporothrix schenckii in Japan. Mycopathologia 116, 9–14 (1991).

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Key words

  • DNA
  • epidemiology
  • mitochondria
  • phylogeny
  • restriction profiles
  • Sporothrix schenckii