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Molecular and General Genetics MGG

, Volume 135, Issue 1, pp 39–44 | Cite as

Biochemical genetics of Coenorhabditis elegans

Article

Summary

A new method of isolating mutants of the free-living nematode Caenorhabditis elegans is described. This method utilises the fluorescence of the nematode as the phenotype. 15 mutants belonging to four genes obtained using this technique have been characterised. Mutants in two of these genes are shown to have blocks in tryptophan catabolism. It is suggested that this method could be used to obtain mutants corresponding to blocks in other metabolic pathways with fluorescent end products.

Keywords

Tryptophan Metabolic Pathway Caenorhabditis Elegans Nematode Caenorhabditis Elegans Biochemical Genetic 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • P. Babu
    • 1
  1. 1.Tata Institute of Fundamental ResearchBombayIndia

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