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Psychopharmacology

, Volume 66, Issue 1, pp 19–22 | Cite as

Effects of propoxyphene, ethoheptazine, and azabicyclane on schedule-controlled responding: Attenuation by pentobarbital but not naloxone

  • J. David Leander
Original Investigations

Abstract

The effects of propoxyphene, ethoheptazine, and azabicyclane, alone and in combination with 1 mg/kg naloxone, were studied in pigeons responding under a multiple fixed ratio, fixed interval schedule of food presentation. Low doses of pentobarbital (3, 5.6, and 10 mg/kg) attenuated the rate-decreasing effects produced by 20 mg/kg propoxyphene, ethoheptazine, and azabicyclane. Naloxone antagonized the rate-decreasing effects produced by 10 mg/kg azabicyclane but did not antagonize the rate-decreasing effects of propoxyphene or ethoheptazine.

Key words

Propoxyphene Ethoheptazine Azabicyclane Naloxone Pentobarbital Schedule-controlled responding 

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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • J. David Leander
    • 1
  1. 1.Department of Pharmacology, School of Medicine, 231HUniversity of North CarolinaChapel HillUSA

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