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Lithium effects on citrate metabolism in humans and rats

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Lithium treatment of manic-depressive patients was accompanied by decreased blood citrate, whereas lithium to rats led to increased blood citrate levels. The implications of these findings for urinary calcium excretion in lithium-treated humans and animals are discussed.

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Correspondence to Erling T. Mellerup.

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Mellerup, E.T., Dam, H., Plenge, P. et al. Lithium effects on citrate metabolism in humans and rats. Psychopharmacology 73, 75–76 (1981). https://doi.org/10.1007/BF00431105

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Key words

  • Lithium
  • Citrate
  • Calcium