Sixteen healthy male subjects classified as sedentary (8) or active (8) exercised to exhaustion on a bicycle ergometer at a load requiring approximately 70% of their aerobic capacity. Biopsy samples were taken from the vastus lateralis at rest and at fatigue. A 12 week training program increased skeletal muscle debranching enzyme activities twofold. Submaximal and maximal exercise to exhaustion resulted in decreased debranching enzyme activities. The results indicate that debranching enzyme activities correlate highly with total phosphorylase activities after submaximal and maximal work to fatigue.
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Supported in part by Grant DNHW 55-04021 from the Department of National Health and Welfare, Ottawa. We thank Miss Diane Tougas and Miss Nancy Smith for technical assistance. This work was completed while A. W. Taylor was under the tenure of a research associateship from the Department of National Health and Welfare, Ottawa. Present address of M. Booth is Departments of Physiology and Physical Education, Queen's University, Kingston, Ontario.
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Taylor, A.W., Stothart, J., Thayer, R. et al. Human skeletal muscle debranching enzyme activities with exercise and training. Europ. J. Appl. Physiol. 33, 327–330 (1974). https://doi.org/10.1007/BF00430240
- Human Skeletal Muscle
- Exercise Training
- Debranching Enzyme