Mammalian Genome

, Volume 5, Issue 11, pp 726–727 | Cite as

Allelic variation of the type 2 tumor necrosis factor receptor gene

  • E. E. Powell
  • L. S. Wicker
  • L. B. Peterson
  • J. A. Todd
Short Communications


Tumor Necrosis Tumor Necrosis Factor Allelic Variation Receptor Gene Tumor Necrosis Factor Receptor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Brennan, F., Feldman, M. (1992). Cytokines in autoimmunity. Curr. Op. Immunol. 4, 754–759.Google Scholar
  2. Drake, C., Babcock, S., Palmer, E., Kotzin, B. (1994). Genetic analysis of the NZB contribution to lupus-like autoimmune disease Proc. Natl. Acad. Sci. USA 91, 4062–4066.Google Scholar
  3. Goodwin, R., Anderson, D., Jerzy, R., Davis, T., Brannan, C., Copeland, N., Jenkins, N., Smith, C. (1991). Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor. Mol. Cell. Biol. 11, 3020–3026.Google Scholar
  4. Heller, R., Song, K., Fan, N., Chang, D. (1992). The p70 tumour necrosis factor receptor mediates cytotoxicity. Cell 70, 47–56.Google Scholar
  5. Hotamisligil, G.S., Shargill, N.S., Spiegelman, B.M. (1993). Adipose expression of tumor necrosis factor-α: direct role in obesitylinked insulin resistance. Science 259, 87–90.Google Scholar
  6. Jacob, C.O., McDevitt, H.O. (1988). Tumour necrosis factor-α in murine autoimmune “lupus” nephritis. Nature 331, 356–358.Google Scholar
  7. Lewis, M., Tartaglia, L.A., Lee, A., Bennett, G.L., Rice, G.C., Wong, G.H.W., Chen, E.Y., Goeddel, D.V. (1991). Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc. Natl. Acad. Sci. USA 88, 2830–2834.Google Scholar
  8. Morahan, G., McClive, P., Huang, D., Little, P., Baxter, A. (1974). Genetic and physiological association of diabetes susceptibility with raised Na+/H+ exchange activity. Proc. Natl. Acad. Sci. USA 91, 5898–5902.Google Scholar
  9. Rodrigues, N., Cornall, R., Chandler, P., Simpson, E., Wicker, L., Peterson, L., Todd, J. (1994). Mapping of an insulin-dependent diabetes locus, Idd9, in NOD mice to Chromosome 4. Mamm. Genome 5, 167–170.Google Scholar
  10. Todd, J.A., Aitman, T.J., Cornall, R.J., Ghosh, S., Hall, J.R.S., Hearne, C.M., Knight, A.M., Love, J.M., McAleer, M.A., Prins, J.-B., Rodrigues, N., Lathrop, G.M., Pressey A., DeLarato, N., Peterson, L.B., Wicker, L.S. (1991). Genetic analysis of autoimmune type 1 diabetes mellitus in mice. Nature 351, 542–547.Google Scholar

Copyright information

© Springer-Verlag New York Inc 1994

Authors and Affiliations

  • E. E. Powell
    • 1
  • L. S. Wicker
    • 2
  • L. B. Peterson
    • 3
  • J. A. Todd
    • 1
  1. 1.Nuffield Department of SurgeryUniversity of Oxford, John Radcliffe HospitalOxfordUK
  2. 2.Merck Research LaboratoriesAutoimmune Diseases, ResearchRahwayUSA
  3. 3.Merck Research LaboratoriesDepartment of Cellular and Molecular PharmacologyRahwayUSA

Personalised recommendations