Molecular and General Genetics MGG

, Volume 175, Issue 2, pp 145–149

Constitutive mutation of cysJIH operon in a cysB deletion strain of Salmonella typhimurium

  • Jack Ostrowski
  • Danuta Hulanicka
Article
  • 38 Downloads

Summary

In a cysB deletion strain a new mutation, denoted cys-2332 was isolated, which causes the constitutive expression of the cysJIH operon. cys-2332 is closely linked to cysJIH and presumably is located in the initiator region of this operon, rendering its expression independent of the cysB gene product and the internal inducer O-acetyl-L-serine. The presence of salfite reductase (encoded by cysI and cysJ) activity in a cysB-cys-2332 double mutant indicates that cysG, which is not linked to cysJIH but is required for the synthesis of the sulfite reductase co-factor siroheme, is not controlled by cysB.

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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • Jack Ostrowski
    • 1
  • Danuta Hulanicka
    • 1
  1. 1.Institute of Biochemistry and BiophysicsPolish Academy of ScienceWarsawPoland

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