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Effects of 8 weeks' endurance training on skeletal muscle metabolism in 56–70-year-old sedentary men

  • H. Suominen
  • E. Heikkinen
  • H. Liesen
  • D. Michel
  • W. Hollmann
Article

Summary

The effects of 8 weeks' endurance training on muscle metabolism at rest and after a submaximal bicycle ergometer exercise were studied in 31 previously sedentary men, aged 56–70. Training consisted of 3–5 one hour exercise bouts per week including walking-jogging, swimming, gymnastics and ball games. The effects of training were similar to those previously reported for younger men. Mean maximal oxygen uptake increased (11%), as did the resting values for muscle glycogen concentration, the enzymes representing aerobic energy metabolism (malate dehydrogenase, succinate dehydrogenase), and also some of the anaerobic enzymes (creatine phosphokinase, lactate dehydrogenase). Lactate production during submaximal work decreased. The enzyme activities were lower following acute exercise both before and after training.

Key words

Enzyme activities Energy metabolism Skeletal muscle Physical training Elderly men 

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References

  1. Adams, G. M., deVries, H. A.: Physiological effects of an exercise training regimen upon women aged 52 to 79. J. Geront. 28, 50–55 (1973)Google Scholar
  2. Åstrand, P.-O., Rodahl, K.: Textbook of work physiology. New York: McGraw-Hill 1970Google Scholar
  3. Barnard, R. J., Peter, J. B.: Effect of training and exhaustion on hexokinase activity of skeletal muscle. J. appl. Physiol. 27, 691–695 (1969)Google Scholar
  4. Bergström, J.: Muscle electrolytes in man. Determination by neutron activation analysis on needle biopsy specimens. A study on normal subjects, kidney patients and patients with chronic diarrhoea. Scand. J. clin. Lab. Invest. 14 (Suppl. 68), 1–110 (1962)Google Scholar
  5. Björntorp, P., Fahlén, M., Holm, J., Schersten, T., Szostak, V.: Determination of succinic oxidase activity in human skeletal muscle. Scand. J. clin. Lab. Invest. 26, 145–150 (1970)Google Scholar
  6. Boström, S., Fahlén, M., Hjalmarson, Å., Johansson, R.: Activities of rat muscle enzymes after acute exercise. Acta physiol. scand. 90, 544–554 (1974)Google Scholar
  7. deVries, H. A.: Physiological effects of an exercise training regimen upon men aged 52 to 88. J. Geront. 25, 325–336 (1970)Google Scholar
  8. Dohm, G. L., Huston, R. L., Askew, E. W., Weiser, P. C.: Effects of exercise on activity of heart and muscle mitochondria. Amer. J. Physiol. 223, 783–787 (1972)Google Scholar
  9. Dohm, G. L., Huston, R. L., Askew, E. W., Fleshwood, H. L.: Effects of exercise, training, and diet on muscle citric acid cycle enzyme activity. Canad. J. Biochem. 51, 849–854 (1973)Google Scholar
  10. Ekblom, B., Åstrand, P.-O., Saltin, B., Stenberg, J., Wallström, B.: Effects of training on circulatory response to exercise. J. appl. Physiol. 24, 518–528 (1968)Google Scholar
  11. Gollnick, P. D., Ianuzzo, D. C., King, D. W.: Ultrastructural and enzyme changes in muscles during exercise. In: Muscle metabolism during exercise. Advances in experimental medicine and biology, Vol. 11 (B. Pernow, B. Saltin, eds.), pp. 69–85. New York: Plenum Press 1971Google Scholar
  12. Gollnick, P. D., Armstrong, R. B., Saltin, B., Saubert, IV, C. V., Sembrowich, W. L., Shepherd, R. E.: Effect of training on enzyme activity and fiber composition of human skeletal muscle. J. appl. Physiol. 34, 107–111 (1973)Google Scholar
  13. Green, D. E., Mii, S., Kohout, P. M.: Studies on the terminal electron transport system. I. Succinic dehydrogenase. J. biol. Chem. 217, 551–567 (1955)Google Scholar
  14. Holloszy, J. O., Molé, P. A., Baldwin, K. M., Terjung, R. L.: Exercise induced enzymatic adaptations in muscle. In: Limiting factors of physical performance (J. Keul, ed.), pp. 66–80. Stuttgart: Thieme 1973Google Scholar
  15. Hollmann, W., Hettinger, Th.: Sportmedizin — Arbeits- und Trainingsgrundlagen, p. 384. Stuttgart-New York: Schattauer 1976Google Scholar
  16. Holm, J., Schersten, T.: Metabolic changes in skeletal muscles after physical conditioning and in peripheral arterial insufficiency. Försvarsmedicin 10, 71–82 (1974)Google Scholar
  17. Hyvärinen, A., Nikkilä, E. A.: Specific determination of blood glucose with o-toluidine. Clin. chim. Acta 7, 140–143 (1962)Google Scholar
  18. Karlsson, J., Nordesjö, L.-O., Jorfeldt, L., Saltin, B.: Muscle lactate, ATP, and CP levels during exercise after physical training in man. J. appl. Physiol. 33, 199–203 (1972)Google Scholar
  19. Karlsson, J., Sjödin, B., Thorstensson, A., Hultén, B., Frith, K.: LDH isozymes in skeletal muscles of endurance and strength trained athletes. Acta physiol. scand. 93, 150–156 (1975)Google Scholar
  20. Kiessling, K.-H., Pilström, L., Bylund, A.-Ch., Saltin, B., Piehl, K.: Enzyme activities amd morphometry in skeletal muscle of middle-aged men after training. Scand. J. clin. Lab. Invest. 33, 63–69 (1974)Google Scholar
  21. Klissouras, V.: Genetic limit of functional adaptability. Int. Z. angew. Physiol. 30, 85–94 (1972)Google Scholar
  22. Liesen, H., Heikkinen, E., Suominen, H., Michel, D.: Der Effekt eines zwölfwöchigen Ausdauertrainings auf die Leistungsfähigkeit und den Muskelstoffwechsel bei untrainierten Männern des 6. und 7. Lebensjahrzehnts. Sportarzt u. Sportmedizin 26, 26–30 (1975)Google Scholar
  23. Liesen, H., Völker, K., Lagerström, D.: Ein körperliches Aufbautraining bei ungeübten älteren Menschen. Geriatrie 6, 147–148 (1976)Google Scholar
  24. Morgan, T. E., Cobb, L. A., Short, F. A., Ross, R., Gunn, D. R.: Effects of long-term exercise on human muscle mitochondria. In: Muscle metabolism during exercise. Advances in experimental medicine and biology, Vol. 11 (B. Pernow, B. Saltin, eds.), pp. 87–95. New York: Plenum Press 1971Google Scholar
  25. Saltin, B.: Metabolic fundamentals in exercise. Med. Sci. Sport. 5, 137–146 (1973)Google Scholar
  26. Saltin, B., Hartley, L. H., Kilbom, Å., Åstrand, I.: Physical training in sedentary middle-aged and older men. II: Oxygen uptake, heart rate and blood lactate concentration at submaximal and maximal exercise. Scand. J. clin. Lab. Invest. 24, 323–334 (1969)Google Scholar
  27. Saltin, B., Karlsson, J.: Muscle glycogen utilization during work of different intensities. In: Muscle metabolism during exercise. Advances in experimental medicine and biology, Vol. 11 (B. Pernow, B. Saltin, eds.), pp. 284–299. New York: Plenum Press 1971Google Scholar
  28. Saltin, B., Wahren, J., Pernow, P.: Phosphagen and carbohydrate metabolism during exercise in trained middle-aged men. Scand. J. clin. Lab. Invest. 33, 71–77 (1974)Google Scholar
  29. Silberberg, R., Stamp, W. G., Lesker, P. A., Hasler, M.: Aging changes in ultrastructure and enzymatic activity of articular cartilage of guinea pigs. J. Geront. 25, 184–198 (1970)Google Scholar
  30. Skinner, J. S.: Age and performance. In: Limiting factors of physical performance (J. Keul, ed.), pp. 271–282. Stuttgart: Thieme 1973Google Scholar
  31. Suominen, H., Heikkinen, E.: Enzyme activities in muscle and connective tissue of M. vastus lateralis in habitually training and sedentary 33 to 70-year-old men. Europ. J. appl. Physiol. 34, 249–254 (1975)Google Scholar
  32. Terjung, R. L., Baldwin, K. M., Molé, P. A., Klinkerfuss, G. H., Holloszy, J. O.: Effect of running to exhaustion on skeletal muscle mitochondria: a biochemical study. Amer. J. Physiol. 223, 549–554 (1972)Google Scholar
  33. Varnauskas, E., Björntorp, P., Fahlén, M., Prerovský, I., Stenberg, J.: Effects of physical training on exercise blood flow and enzymatic activity in skeletal muscle. Cardiovasc. Res. 4, 413–422 (1970)Google Scholar

Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • H. Suominen
    • 1
    • 2
  • E. Heikkinen
    • 1
    • 2
  • H. Liesen
    • 1
    • 2
  • D. Michel
    • 1
    • 2
  • W. Hollmann
    • 1
    • 2
  1. 1.Department of Public HealthUniversity of JyväskyläJyväskyläFinland
  2. 2.Institute for Sports-Medicine and CardiologyGerman Sports UniversityCologneFederal Republik of Germany

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