Aneurysms experimentally induced by using the silver nitrate coagulation method in 10 Wistar Albino rats are wrapped with Polyglactin 910 and Fibrin Sealant. 6 weeks later the rats are sacrificed and compared with the control group. In the group in which Polyglactin 910 and Fibrin Sealant were used as the wrapping material, non-specific inflammatory granulation tissue development around the ancurysms is observed. We suggest that a Polyglactin 910 and Fibrin Sealant combination can be used as a wrapping material in the treatment of aneurysms where clipping is not possible.
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Uzan, M., Hanci, M., Kuday, C. et al. A new aneurysm wrapping material: polyglactin 910+fibrin sealant. Neurosurg. Rev. 19, 89–91 (1996). https://doi.org/10.1007/BF00418076