Abstract
Aneurysms experimentally induced by using the silver nitrate coagulation method in 10 Wistar Albino rats are wrapped with Polyglactin 910 and Fibrin Sealant. 6 weeks later the rats are sacrificed and compared with the control group. In the group in which Polyglactin 910 and Fibrin Sealant were used as the wrapping material, non-specific inflammatory granulation tissue development around the ancurysms is observed. We suggest that a Polyglactin 910 and Fibrin Sealant combination can be used as a wrapping material in the treatment of aneurysms where clipping is not possible.
Similar content being viewed by others
References
Black SPW, WJ German: Observations on the relationships between the volume and size of the orifice of experimental aneurysms. J Neurosurg 17 (1960) 984–990
Dott NM: Intracranial aneurysms: cerebral arteriography; surgical treatment. Edinb Med J 40 (1930) 219–234
Ebina K, T Iwabuchi, S Suzuki: A clinico-experimental study on various wrapping materials of cerebral aneurysms. Acta Neurochir 72 (1984) 61–71
German WJ, SPW Black: Experimental production of carotid aneurysms. N Eng J Med 250 (1954) 104–106
Hashimoto N, H Handa, F Hazama: Experimentally induced aneurysms in rats. Surg Neurol 11 (1979) 243–247
Hassler O: Experimental carotid ligation followed by aneurysmal formation and other morphological changes in the circle of Willis. J Neurosurg 20 (1963) 1–7
Nishikawa M, RD Smith, Y Yonekawa: Experimental intracranial aneurysms. Surg Neurol 7 (1977) 241–244
Sachs E Jr: The fate of muscle and cotton wrapped about intracranial carotid arteries and aneurysms: A laboratory and clinicopathological study. Acta Neurochir 26 (1972) 121–137
Sadasivan B, S Ma, M Dujovny, KL Ho, JI Ausman: Use of experimental Aneurysms to evaluate wrapping materials. Surg Neurol 34 (1990) 3–7
Shamsi AA: AgNo3 Koagülasyon Yöntemi ile Deneysel Anevrizma Olusturulmasi (Doctoral Dissertation) Istanbul, Turkey, 1991
Yaşargil MG: Addendum in Microneurosurgery Vol. 2 Georg Thieme Verlag, Stuttgart 1984
Young Ph, MG Yasargil: Experimental carotid artery aneurysms in rats: a new model for microsurgical practice. J Microsurg 3 (1982) 135–146