Control of morphine-withdrawal hypothermia by conditional stimuli
Male rats were given increasing doses of morphine sulfate to cause addiction. Each injection was paired with a bell. After a number of pairings, the bell acquired conditional-stimulus property in that, like morphine, it prevented withdrawal hypothermia during 72 h of withholding morphine. In another group the withdrawal hypothermia was precipitated by withholding of morphine injections. The bell reversed that hypothermia.
Key wordsNarcotic Addiction Conditional Stimulus Hypothermia Narcotic Withdrawal Morphine
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